Proteomic study on gender differences in aging kidney of mice |
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Authors: | Hanna Amelina Susana Cristobal |
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Affiliation: | (1) Department of Biochemistry and Biophysics, Stockholm University, SE-106 91 Stockholm, Sweden |
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Abstract: | Background This study aims to analyze sex differences in mice aging kidney. We applied a proteomic technique based on subfractionation, and liquid chromatography coupled with 2-DE. Samples from male and female CD1-Swiss outbred mice from 28 weeks, 52 weeks, and 76 weeks were analysed by 2-DE, and selected proteins were identified by matrix assisted laser desorption ionisation time-of-flight mass spectrometry (MALDI-TOF MS). |
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