| From stem cells to red blood cells:how far away from the clinical application? |
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| 作者姓名： | XIE XiaoYan LI YanHua PEI XueTao |
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| 作者单位： | Stem Cell and Regenerative Medicine Lab,Beijing Institute of Transfusion Medicine;South China Research Center for Stem Cell and Regenerative Medicine |
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| 基金项目： | supported by the National High Technology Research and Development Program of China(2013AA020107);National Basic Research Program of China(2011CB964804);National Natural Science Foundation of China(31101040) |
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| 摘 要： | The generation of red blood cells(RBCs)from stem cells provides a solution for deficiencies in blood transfusion.Currently,primary hematopoietic stem cells,embryonic stem cells and induced pluripotent stem cells have shown the potential to produce fully mature RBCs.Here,we discuss the advantages,induction protocols,progress and possible clinical applications of stem cells in RBC production.
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| 关 键 词： | stem cells red blood cells differentiation clinical application |
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