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Importance of thymus-derived lymphocytes in cell-mediated immunity to infection |
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| Authors: | R J North |
| Institution: | 1. Immunology, World Health Organization, 1211 Geneva 27, Switzerland;2. The San Francisco V.A. Hospital U.S.A.;3. The Laboratory of Radiobiology, University of California Medical Centre, San Francisco, California 94122, USA;4. Section of Haematology and Immunology, University of California Medical Centre, San Francisco, California 94122, USA;5. Department of Anatomy, Hebrew University-Hadassah Medical School, Jerusalem, Israel |
| Abstract: | Peripheral blood lymphocytes from ten human neonates and ten adults were studied. Many more medium and large cells were identified in neonates, and the ultrastructure of the medium-sized lymphocytes resembled guinea pig transitional cells. There were 20 times more nucleoside-incorporating lymphocytes in the newborn samples, and a neonatal high-labeling cell was identified. |
| Keywords: | Reprint requests: Prof H Hugh Fudenberg Section of Haematology and Immunology Univ of California Medical Center San Francisco CA 94122 |
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