首页 | 本学科首页   官方微博 | 高级检索  
     


Estimation of a common odds ratio in case-control studies of familial aggregation
Authors:A Donner  W Hauck
Affiliation:Department of Epidemiology and Biostatistics, University of Western Ontario, London, Canada.
Abstract:A new estimator of a common odds ratio is proposed for case-control studies of familial aggregation. The proposed estimator is a modification to the usual Mantel-Haenszel estimator that relies on an empirical adjustment for the within-family clustering which is typical of such designs. A simulation study shows that the estimator tends to have smaller mean squared error than the unmodified Mantel-Haenszel estimator under conditions likely to arise in practice. The construction of confidence intervals is also discussed.
Keywords:
设为首页 | 免责声明 | 关于勤云 | 加入收藏

Copyright©北京勤云科技发展有限公司  京ICP备09084417号