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费氏链霉菌HTP6分批发酵动力学
引用本文:张新刚,史冠莹,陶 科,滕 云,崔文华,刘 运,全 鑫,侯太平.费氏链霉菌HTP6分批发酵动力学[J].微生物学通报,2009,36(3):0311-0315.
作者姓名:张新刚  史冠莹  陶 科  滕 云  崔文华  刘 运  全 鑫  侯太平
作者单位:四川大学生命科学学院,四川,成都,610064;四川大学生物资源与生态环境教育部重点实验室,四川,成都,610064
基金项目:国家863计划项目(No. 2006AA10A209); 国家自然科学基金(No. 30800034)
摘    要:对费氏链霉菌HTP6产新霉素的分批发酵动力学进行了研究, 并建立了动力学模型。对数生长期最大比生长速率μm为0.0866 h-1, 产物合成期最大合成速率qp为1.1867×10-4 g/(mL×h)。对实验数据与模型模拟值进行拟合检验, 表现出很好的适用性, 实验平均相对偏差小于5%。表明该动力学模型对费氏链霉菌产新霉素的发酵生产具有实际意义。

关 键 词:费氏链霉菌    新霉素    发酵    动力学模型

Kinetics of Streptomyces fradiae HTP6 in the Batch Fermentation Process
ZHANG Xin-Gang,SHI Guan-Ying,TAO Ke,TENG Yun,CUI Wen-Hu,LIU Yun,QUAN Xin and HOU Tai-Ping.Kinetics of Streptomyces fradiae HTP6 in the Batch Fermentation Process[J].Microbiology,2009,36(3):0311-0315.
Authors:ZHANG Xin-Gang  SHI Guan-Ying  TAO Ke  TENG Yun  CUI Wen-Hu  LIU Yun  QUAN Xin and HOU Tai-Ping
Institution:(1. College of Life Sciences, Sichuan University, Chengdu, Sichuan 610064, China)(2. Key Laboratory of Bio-resources and Eco-environment, Ministry of Education, Chengdu, Sichuan 610064, China);(1. College of Life Sciences, Sichuan University, Chengdu, Sichuan 610064, China)(2. Key Laboratory of Bio-resources and Eco-environment, Ministry of Education, Chengdu, Sichuan 610064, China);(1. College of Life Sciences, Sichuan University, Chengdu, Sichuan 610064, China)(2. Key Laboratory of Bio-resources and Eco-environment, Ministry of Education, Chengdu, Sichuan 610064, China);(1. College of Life Sciences, Sichuan University, Chengdu, Sichuan 610064, China)(2. Key Laboratory of Bio-resources and Eco-environment, Ministry of Education, Chengdu, Sichuan 610064, China);(1. College of Life Sciences, Sichuan University, Chengdu, Sichuan 610064, China)(2. Key Laboratory of Bio-resources and Eco-environment, Ministry of Education, Chengdu, Sichuan 610064, China);(1. College of Life Sciences, Sichuan University, Chengdu, Sichuan 610064, China)(2. Key Laboratory of Bio-resources and Eco-environment, Ministry of Education, Chengdu, Sichuan 610064, China);(1. College of Life Sciences, Sichuan University, Chengdu, Sichuan 610064, China)(2. Key Laboratory of Bio-resources and Eco-environment, Ministry of Education, Chengdu, Sichuan 610064, China);(1. College of Life Sciences, Sichuan University, Chengdu, Sichuan 610064, China)(2. Key Laboratory of Bio-resources and Eco-environment, Ministry of Education, Chengdu, Sichuan 610064, China)
Abstract:
Keywords:Streptomyces fradiae  Neomycin  Fermentation  Kinetics model
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