| 新疆雪莲的高效液相指纹图谱及液-质联用分析 |
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| 引用本文： | 王晓玲,蔡敏,周燕,丁立生.新疆雪莲的高效液相指纹图谱及液-质联用分析[J].天然产物研究与开发,2006,18(4):624-627. |
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| 作者姓名： | 王晓玲 蔡敏 周燕 丁立生 |
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| 作者单位： | 1. 西南民族大学少数民族药物研究所;中国科学院成都生物研究所,成都,610041
2. 中国科学院成都生物研究所,成都,610041 |
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| 摘 要： | 建立新疆雪莲药材的高效液相指纹图谱。以Luna C18为分析柱,用乙腈-0.1%醋酸梯度洗脱,获得分离度较好的新疆雪莲药材HPLC分析条件。通过10批样品的分析和对照,标示出12个共有峰,相似度分析大于0.92。最后通过HPLC-UV-MS/MS联用分析鉴定出其中7个化学成分。该方法可为新疆雪莲药材指纹图谱和质量分析方法的建立提供参考。
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| 关 键 词： | 新疆雪莲 指纹图谱 高效液相 液-质联用 |
| 文章编号： | 1001-6880（2006）04-0624-04 |
| 收稿时间： | 2005-03-03 |
| 修稿时间： | 2005-04-18 |
HPLC Fingerprint and HPLC-MS/MS Analysis for the Aerial Parts of Saussurea involucrate |
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| WANG Xiao-ling,CAI Min,ZHOU Yan,DING Li-sheng.HPLC Fingerprint and HPLC-MS/MS Analysis for the Aerial Parts of Saussurea involucrate[J].Natural Product Research and Development,2006,18(4):624-627. |
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| Authors: | WANG Xiao-ling CAI Min ZHOU Yan DING Li-sheng |
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| Institution: | 1. Institute of National Medicine, Southwest University of Nationlities ; 2. Chengdu Institute of Biology, Chinese Academic of Sciences, Chengdu 610041 ,China |
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| Abstract: | The HPLC fingerprint spectrum of the aerial parts of Saussurea involucrate Kar.et Kir.was established.The HPLC analysis was performed on a Luna C_(18) column with the eluting system of gradient acetonitrile and 0.1%CH_3COOH.Twelve main characteristic peaks were selected from the fingerprint spectrum of 10 barches of samples.The characteristic peaks were qualitatively analyzed by HPLC-UV-MS/MS,7 of which were identified based on the UV and MS/MS spectra of each analyte with that of authentic compounds and literature data.This method can be utilized in the fingerprinting and quality control of the crude drug of S.involucrate |
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| Keywords: | Saussurea involucrate fingerprint HPLC LC-MS |
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