| 人染色体脆性位点部位的显微光谱学研究
Study of Microspectroscopy for the Position of the Fragile Sites in Human Chromosome |
| |
| 引用本文： | 王晓云 吴 海 张丰德 岳慧琴 WANG Xiao-Yun,WU Hai,ZHANG Feng-De,YUE Hui-Qin.人染色体脆性位点部位的显微光谱学研究
Study of Microspectroscopy for the Position of the Fragile Sites in Human Chromosome[J].遗传,1994,16(1):1-4. |
| |
| 作者姓名： | 王晓云 吴 海 张丰德 岳慧琴 WANG Xiao-Yun WU Hai ZHANG Feng-De YUE Hui-Qin |
| |
| 作者单位： | 天津儿童医院儿科研究所!300074，天津儿童医院儿科研究所!300074，南开大学生物系!天津，300071，南开大学生物系!天津，300071 |
| |
| 摘 要： | 采用显微分光光度法，对染色体脆性位点的部位进行了显微光谱学研究。实验证明，带有脆点的染色体其DNA含量大多数趋向减少，少数略有增加，推测染色体脆性部位的产生是由于染色质DNA在高度凝缩形成中期染色体过程中超旋结构改变的结果。
The position of fragile sites in human chromosome was studied by means of the microspectroscopy. The results show that the amount DNA in chromosome with fragile sites decreases in most condition. We can suppose that the fragile sites of chromosome is caused by the superhelix structure changes of chromosome DNA during the formation of metaphase chromosome which is formed in high condensation.
|
| 关 键 词： | 人染色体 脆性位点 显微光谱学 human chromosome fragile sites microspectroscopy |
Study of Microspectroscopy for the Position of the Fragile Sites in Human Chromosome |
| |
| Wang Xiaoyun, Wu Hai.Study of Microspectroscopy for the Position of the Fragile Sites in Human Chromosome[J].Hereditas,1994,16(1):1-4. |
| |
| Authors: | Wang Xiaoyun Wu Hai |
| |
| Abstract: | The position of fragilc sites in human chromosome was studied by means of the microspectroscopy. The results show that the amount of DNA in chromosome with fragile sites decreasesin most condition. We can suppose that the fragile sites of chromosome is caused by the superhelix structure changes of chromatin DNA during the formation of metaphase chromosome which is formed in high condensation. |
| |
| Keywords: | Human chromosomc Fragile sites Microspectroscopy |
| 本文献已被 CNKI 维普 等数据库收录！ |
| 点击此处可从《遗传》浏览原始摘要信息 |
| 点击此处可从《遗传》下载免费的PDF全文 |
