|
|||||
|
|
A simple integrative electrophysiological model of bursting GnRH neurons |
|
| Authors: | Dávid Csercsik Imre Farkas Erik Hrabovszky Zsolt Liposits |
| Institution: | 1. Process Control Research Group, Computer and Automation Research Institute, Hungarian Academy of Sciences, P.O. Box 63, 1518, Budapest, Hungary 2. Department of Endocrine Neurobiology, Institute of Experimental Medicine, Hungarian Academy of Sciences, P.O. Box 67, 1450, Budapest, Hungary 3. Faculty of Information Technology, P??zm??ny P??ter Catholic University, P.O. Box 178, 1364, Budapest, Hungary |
| Abstract: | In this paper a modular model of the GnRH neuron is presented. For the aim of simplicity, the currents corresponding to fast time scales and action potential generation are described by an impulsive system, while the slower currents and calcium dynamics are described by usual ordinary differential equations (ODEs). The model is able to reproduce the depolarizing afterpotentials, afterhyperpolarization, periodic bursting behavior and the corresponding calcium transients observed in the case of GnRH neurons. |
| Keywords: | |
| 本文献已被 PubMed SpringerLink 等数据库收录！ | |