FUGE: an analytical ultracentrifuge simulation for teaching purposes |
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Authors: | Mynett Alan |
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Institution: | Brighton Centre for Advanced Biology, Brighton College of Technology, Department of Applied Science Pelham Street, Brighton BN1 4FA, UK |
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Abstract: | An IBM-compatible microcomputer program for teaching purposesis described which simulates the operation of a sedimentationvelocity determination of a protein in an analytical ultracentrifugeusing schlieren optics. The program operates in speeded-up timeand simulates the major procedures which would need to be carriedout to operate such an instrument. The position of the sedimentingboundary can be observed at any time during the run, and upto six photographs can be recorded for subsequentanalysis. Calculation of sedimentation coefficient, diffusioncoefficient and mol. wt can be made from a dot-matrix printout.Ten representative proteins are stored within the program, butprovision exists for user-supplied data.
Received on June 25, 1987; accepted on September 9, 1987 |
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