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Enzymatic resolutions of α- and β-hydroxypropionic acid esters
Authors:M Gruber-Khadjawi  H Hnig  H Weber
Institution:M. Gruber-Khadjawi,H. Hönig,H. Weber
Abstract:The synthesis of some acyloxy-methoxy-cinnamic acid derivatives, azidohydroxy butanoates, and azidohydroxy butanedioates in enantiomerically pure form is presented. Racemic diastereomerically pure educts were prepared in few steps. These racemates are resolved with lipases from Candida cylindracea (CC) and Pseudomonas fluorescens (P).
Keywords:dihydrocinnamic acid derivatives  hydroxy azido acids  hydroxy amino acids  enantioselective hydrolysis  Pseudomonas fl  lipase  Candida cyclindracea lipase
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