Multiple genes are transcribed in Hordeum vulgare and Zea mays that carry the DNA binding domain of the myb oncoproteins |
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Authors: | Adriano Marocco Margit Wissenbach Dieter Becker Javier Paz-Ares Heinz Saedler Francesco Salamini and Wolfgang Rohde |
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Institution: | (1) Max-Planck-Institut für Züchtungsforschung, D-5000 Köln 30, Federal Republic of Germany |
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Abstract: | Summary cDNA clones were isolated from tissue specific cDNA libraries of barley and maize using as a probe the cDNA of the maize gene C1, a regulator of anthocyanin gene expression. C1-related homology for all of the four cDNAs characterized by sequence analysis is restricted to the N-terminal 120 amino acids of the putative proteins. This region shows striking homology to the N-proximal domain of the myb oncoproteins from vertebrates and invertebrates. Within the myb proto-oncogene family this part of the respective gene products functions as a DNA binding domain. Acidic domains are present in the C-proximal protein segments. Conservation of these sequences, together with the genetically defined regulator function of the C1 gene product, suggest that myb-related plant genes code for trans-acting factors which regulate gene expression in a given biosynthetic pathway. |
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Keywords: | Plant genes myb proto-oncogene homoloy |
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