Outer-membrane permeability to beta-lactam antibiotics in Yersinia enterocolitica |
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| Authors: | K Brzostek J Hrebenda |
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| Institution: | Institute of Microbiology, Warsaw University, Poland. |
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| Abstract: | Two outer-membrane (OM) proteins of Yersinia enterocolitica YOMP-C and YOMP-F appear to function as porins. Mutants that were YOMP-C- and YOMP-F- exhibited changes in cephaloridine and 3H]glucose uptake and increased resistance to beta-lactam antibiotics (especially cephalosporins) and tetracycline. Alterations in OM permeability may contribute to antibiotic resistance in Yersinia. |
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