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A microwave promoted and Lewis acid catalysed solventless approach to 4-azasteroids |
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| Authors: | Borthakur Moyurima Boruah Romesh C |
| Institution: | aMedicinal Chemistry Division, North-East Institute of Science and Technology, Jorhat 785006, Assam, India |
| Abstract: | The preparation of 3-oxo-4-azasteroid from A-nor-3,5-secosteroid-3-oic acid is described in a solventless condition catalysed by Lewis acid under microwave irradiation. We utilized urea as an environmentally benign source for the generation of ammonia for the aza cyclization reaction. |
| Keywords: | 4-Azasteroids Urea Lewis acid Microwave |
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