肿瘤患者痰培养中细菌谱及耐药性的研究

目的评价肿瘤患者治疗过程中细菌感染的病原种类分布及其耐药情况，从而达到为肿瘤患者的抗感染治疗提供依据。方法对321例肿瘤患者痰标本培养及药敏结果进行分析。结果321例肿瘤患者痰标本检出致病菌（含条件致病菌）435株，革兰阴性杆菌占69．7％，革兰阳性球菌占26．2％，念珠菌占4．1％．5种主要致病菌对常用的抗生素存在不同程度耐药．产超广谱β-内酰胺酶细菌18株，耐甲氧西林葡萄球菌9株。结论对于肿瘤患者的抗感染治疗．临床上应重视细菌的种类分布，细菌的耐药问题，合理使用抗生素。

Study of sputum culture for Germ and drug resistance of patients with cancer

Objective To study the pathogen of respiratory system infection and drug resistance in patients with cancer.Methods To analyse the culture results of 321 sputum specimen from patients with cancer.Results 435 strains pathogens(include condition cause disease germ) had been detected from 321 sputum specimen,in which G~-bacillus,G~+ coccus and candida account for 69.7%,26.2%and 4.1%,and 5 kinds of condition cause disease germ showed resistance to common antibiotic at different level.We also screened out 18 strains pathogens which produce extend spectrum bate-lactamases and 9 strains of methiclinllin-resitant Staphylococcus aureus.Conclusion It was advantaged for clinical treatment to determine the pathogen of respiratory system infection and carry out drug resistant test in patients with cancer.