Oligomerization aiming at phosphonate analogues of oligoadenylates |
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| Authors: | Pressová Martina Liboska Radek Budesínský Milos Králíková Sárka Kavenová Ivana Rosenberg Ivan |
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| Affiliation: | Institute of Organic Chemistry and Biochemistry, Academy of Sciences, Prague, Czech Republic. |
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| Abstract: | This work deals with isopolar, phosphonate-based nucleotide analogues containing a bridging P-C bond instead of the ester P-O linkage. Specifically, starting from activated derivatives 1, 2, and 3, a simple process for preparation of mixtures of short oligomers and their analyses were elaborated. |
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