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Bi- and tricyclic nucleoside derivatives restricted in S-type conformations and obtained by RCM-reactions
Authors:Albaek Nanna  Ravn Jacob  Freitag Morten  Thomasen Helena  Christensen Nanna K  Petersen Michael  Nielsen Poul
Affiliation:Nucleic Acid Center, Department of Chemistry, University of Southern Denmark, Odense M, Denmark.
Abstract:
Ring-closing metathesis (RCM) is applied as a new and powerful technology in the construction of nucleoside analogues that are conformationally restricted in S-type conformations due to additional 3',4'- and/or 3',5'-linkages.
Keywords:
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