A new tiazofurin pronucleotide: synthesis and biological evaluation of cyclosaligenyl-tiazofurin monophosphate |
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| Authors: | Cappellacci L Barboni G Franchetti P Martini C Jayaram H N Grifantini M |
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| Institution: | Department of Chemical Sciences, University of Camerino, Camerino, MC, Italy. |
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| Abstract: | Synthesis and biological activities of cyclosaligenyl-tiazofurin monophosphate (CycloSal-TRMP), a new tiazofurin pronucleotide, are reported. CycloSal-TRMP proved to be active in vitro against human myelogenous leukemia K562 cell line and as A1 adenosine receptor agonist. |
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