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Influence of Actovegin on proliferation of transplanted cell lines
Authors:A K Gulevskii  A V Trifonova  A A Lavrik
Institution:(1) Institute of Problems of Cryobiology and Cryological Medicine, National Academy of Sciences of Ukraine, ul. Pereyaslavskaya 23, Kharkov, Ukraine;(2) Institute of Experimental and Clinical Veterinary Medicine (National Scientific Center), ul. Pushkinskaya 83, Kharkov, Ukraine
Abstract:The influence of the drug Actovegin on the proliferative activity and mitotic regime of cells of transplanted RK-15-1EKVM and VNK-21 clone 13/04 lines is studied. The stimulating effect of the drug on cell proliferation when added to a growth medium containing cattle blood serum of differing compositions and at different concentrations is demonstrated. It is concluded that Actovegin shows promise for use in bioengineering of cell cultures.
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