Internal calcium-binding proteins |
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| Authors: | C W Heizmann B W Sch?fer |
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| Affiliation: | Department of Pediatrics, University of Zürich, Switzerland. |
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| Abstract: | Ca(2+)-ions play a key role in the regulation of many cellular processes and impairment of calcium homeostasis has been implicated in several diseases. Intracellularly the Ca(2+)-signal is transmitted by two families of proteins, the 'EF-hand'- and the Ca(2+)-dependent and phospholipid binding proteins. Their protein and gene structures as well as possible functional roles are summarized. |
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