口腔微生物群和人体健康

口腔微生物群作为人体微生物群的重要组成部分,其与人体健康之间的关系已成为各领域研究的焦点。口腔微生物群种类繁多、组成复杂,涵盖了细菌、真菌、古细菌和病毒等。近年来的研究显示,口腔微生物群的组成和比例与人体健康密切相关,会影响口腔疾病如龋齿、牙周病的发生。同时口腔微生物也是全身系统性疾病如肺炎、肿瘤和糖尿病等发生的危险因素之一。大量研究认为,口腔微生物群组成的改变、口腔微生物群之间的相互作用对疾病的发生有协同促进作用。本文聚焦于口腔微生物群的组成相关研究、口腔微生物组的最新进展,并对其与人体健康之间的关系进行综述。

Oral microbiota and human health

Abstract: As one of the most important part of human microbiota, the oral microbiota is composed of microorganisms, including bacteria, fungi, archaea and viruses. Increasing evidence suggested that the structure and composition of oral microbiota are closely related to the development of two commonest oral diseases i.e. dental caries and periodontal diseases, and also present significant risk factors of human health conditions, such as tumor, diabetes, etc. It is widely accepted that oral microorganisms cause diseases mainly in a synergistic or cooperative way. This review summarized oral microbiota composition and the relationship between oral microbiota and diseases.