Hyperplastic cellular components of a hemangiopericytoma. An ultrastructural study |
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Authors: | T Maruyama T Nomiyama M Asahi N Mori E Ono A Kawahara S Fujimoto |
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Institution: | Department of Dermatology, University of Occupational and Environmental Health, School of Medicine, Kitakyushu, Japan. |
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Abstract: | Based on ultrastructural features of cellular components of a hemangiopericytoma, hyperplastic cells are classifiable into fibroblast-like (group I), endotheloid (group II) and pericyte-like (group III) cells. The transformation of the group I cells to the group II, or to the group III cells, is pronounced in our electron micrographs and this may imply that the group I cell is the principal cell of origin in this neoplasm. The smooth muscle-like (group IV) cells comprising the media of the arteries and veins in this neoplasm may represent modified, possibly de-differentiated smooth muscle cells reacted to the neoplastic proliferation of the surrounding adventitial (group I) cells. |
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