| PCI围术期消化道出血患者抗血小板治疗调整及近期疗效 |
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| 引用本文： | 陶杰,韩雅玲,王效增,荆全民,王守力,马颖艳,王耿,栾波,王斌. PCI围术期消化道出血患者抗血小板治疗调整及近期疗效[J]. 现代生物医学进展, 2010, 10(24) |
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| 作者姓名： | 陶杰 韩雅玲 王效增 荆全民 王守力 马颖艳 王耿 栾波 王斌 |
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| 作者单位： | 沈阳军区总医院心内科,辽宁,沈阳,110840 |
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| 摘 要： | 目的:探讨经皮冠状动脉介入治疗(PCI)围术期发生消化道出血(GIB)患者抗血小板治疗的调整,评价其安全性及近期疗效。方法:回顾性分析2005年1月至2008年12月PCI围术期发生GIB的40例患者的临床资料,其中急性心肌梗死(AMI)22例(55%),不稳定型心绞痛18例(45%)。PCI围术期发生GIB的患者,除扩容、输血、抑酸、保护胃粘膜等支持疗法外,依据临床情况调整抗血小板药物。观察住院期间及术后3个月后主要不良心脑事件(MACCE:包括心绞痛、非致死性心肌梗死、心性死亡、再次血管重建、支架内血栓形成、缺血性卒中)及消化道再次出血的发生率。结果:40例患者PCI成功39例(病例成功率97.5%),1例慢性完全闭塞(CTO)病变导丝未通过,1例(2.5%)AMI患者PCI术后第5天发生支架内亚急性血栓(SAT)。出院后3月内,2例未完全血运重建的患者有心绞痛发作,无死亡,所有患者均无消化道再次出血,MACCE发生率(7.5%)。结论:PCI围术期发生GIB的患者,依据临床情况调整抗血小板药物,不增加MACCE风险及消化道再次出血发生率。
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| 关 键 词： | 冠状动脉疾病 经皮冠状动脉内成形术 消化道出血 血小板聚集抑制剂 |
Effects of anti-platelet drugs adjustment on patients with gastrointestinal bleeding undergoing percutaneous coronary intervention |
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| TAO Jie,HAN Ya-ling,WANG Xiao-zeng,JING Quan-min,WANG Shou-li,MA Ying-yan,WANG Geng,LUAN Bo,WANG Bin. Effects of anti-platelet drugs adjustment on patients with gastrointestinal bleeding undergoing percutaneous coronary intervention[J]. Progress in Modern Biomedicine, 2010, 10(24) |
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| Authors: | TAO Jie HAN Ya-ling WANG Xiao-zeng JING Quan-min WANG Shou-li MA Ying-yan WANG Geng LUAN Bo WANG Bin |
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| Affiliation: | TAO Jie,HAN Ya-ling,WANG Xiao-zeng,JING Quan-min,WANG Shou-li,MA Ying-yan,WANG Geng,LUAN Bo,WANG Bin (Department of Cardiology,General Hospital of Shenyang Command,Shenyang 110840,China) |
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| Abstract: | Objective: To explore the adjustment of anti-platelet drugs in patients who underwent gastrointestinal bleeding(GIB) during percutaneous coronary intervention(PCI) perioperative period,and evaluate its short-term efficacy and safety.Methods: The clini-cal data of 40 patients who suffered GIB during PCI perioperative period admitted during January 2005 to December 2008 were retro-spectively analyzed.22(55 %) was diagnosed as acute myocardial infarction and 18(45 %) as unstable angina pectoris.Anti-platelet d... |
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| Keywords: | Coronary disease Percutaneous transcoronary angioplasty Gastrointestinal hemorrhage Platelet aggregation inhibitors |
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