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尿激酶介入动脉溶栓治疗26例急性脑梗死临床分析
引用本文:陈光辉,叶飞,秦碧勇,席刚明.尿激酶介入动脉溶栓治疗26例急性脑梗死临床分析[J].现代生物医学进展,2010,10(24).
作者姓名:陈光辉  叶飞  秦碧勇  席刚明
作者单位:湖北医药学院附属人民医院(十堰市人民医院)神经内科,湖北,十堰,442000
摘    要:目的:观察缺血性脑梗死急性期尿激酶介入动脉溶栓治疗的临床疗效。方法:应用尿激酶早期动脉内溶栓治疗急性脑梗死26例。溶栓前及溶栓后2 h、30 d进行神经功能缺损评分,同时观察并发症及疗效。结果:颈内动脉闭塞9例,大脑中动脉主干(M1)段闭塞6例,大脑前动脉闭塞4例,椎基底动脉系统闭塞3例。溶栓治疗后10例获得完全再通,9例部分再通,3例未开通。临床症状完全恢复及明显好转16例,占总病例61.5%。术后NIHSS评分较术前明显提高。并发颅内出血1例。再通后发生再闭塞1例。结论:尿激酶动脉溶栓治疗急性脑梗死安全、有效、可行,但其远期疗效还需进一步观察。

关 键 词:脑梗死  脑卒中  动脉溶栓  尿激酶  

Effect of Interventional Intra-arterial Thrombolysis with Urokinase on Patients with Acute Cerebral Infarction
CHEN Guang-hui,YE Fei,QIN Bi-yong,XI Gang-ming.Effect of Interventional Intra-arterial Thrombolysis with Urokinase on Patients with Acute Cerebral Infarction[J].Progress in Modern Biomedicine,2010,10(24).
Authors:CHEN Guang-hui  YE Fei  QIN Bi-yong  XI Gang-ming
Institution:CHEN Guang-hui,YE Fei,QIN Bi-yong,XI Gang-ming(Department of neurology,Renmin Hospital of Shiyan(Hospital affiliated to Hubei Medical and pharmaceutical College,Hubei Shiyan 442000,China)
Abstract:Objective: To investigate the clinical efficacy of intra-arterial thrombolysis with urokinase in treating acute ischemic cerebral infarction.Methods: 26 patients with acute cerebral infarction were treated with urokinase in the early stage.The neurological impairment score before the treatment and 2 hours,30 days after the treatment were evaluated.The incidence of complications,the thera-peutic effects were observed and the treatment experience was also summarized.Results: Nine patients had internal carotid...
Keywords:Cerebral infarction  Stroke  Arterial thrombolysis  Urokinase  
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