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| 欧亚旋覆花总黄酮提取与富集工艺研究 | |
| 引用本文： | 耿红梅,张嫡群,王云志,祁金龙,杨双革. 欧亚旋覆花总黄酮提取与富集工艺研究[J]. 天然产物研究与开发, 2006, 18(4): 643-646 |
| 作者姓名： | 耿红梅 张嫡群 王云志 祁金龙 杨双革 |
| 作者单位： | 河北医科大学新药开发研究室,石家庄,050017 |
| 基金项目： | 河北省自然科学基金项目(303470) |
| 摘 要： | 为研究欧亚旋覆花总黄酮的最佳提取与大孔吸附树脂富集工艺,采用不同溶剂、多种提取方法、L9(34)正交实验优化及AB-8大孔吸附树脂富集,结果表明其最佳提取工艺为用10倍量水为溶剂回流提取3次,每次1h,再结合AB-8大孔吸附树脂富集,以70%乙醇洗脱效果最佳,总黄酮回收率达90%,总黄酮含量达50%以上。此工艺简便可行,符合工业化生产要求。 |
| 关 键 词： | 欧亚旋覆花 总黄酮 大孔树脂 正交设计 |
| 文章编号： | 1001-6880（2006）04-0643-04 |
| 收稿时间： | 2005-11-04 |
| 修稿时间： | 2005-12-19 |
Extraction and Enrichment of Total Flavonoids in Inula britannica L. |
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| GENG Hong-mei,ZHANG Di-qun,WANG Yun-zhi,QI Jin-long,YANG Shuang-ge. Extraction and Enrichment of Total Flavonoids in Inula britannica L.[J]. Natural Product Research and Development, 2006, 18(4): 643-646 | |
| Authors: | GENG Hong-mei ZHANG Di-qun WANG Yun-zhi QI Jin-long YANG Shuang-ge |
| Affiliation: | Development Department of New Drugs of Hebei Medical University, Shijiazhuang 050017, China |
| Abstract: | The process of extracting total flavonoids from Inula britannica L.and of enriching them with macroporous resins was studied.The extraction process was optimized by orthogonal design.The total flavonoids were enriched by AB-8 macroporous resins.The results indicated that the optimum process was to extract 3 times(each one hour)at reflux with 10:1 water:materials and the total flavonoids were enriched with AB-8 macroporous resins and eluted by 70% ethanol.The recovery rate of total flavonoids was above 90%.The extraction procedure was applicable to industrial production. |
| Keywords: | Inula britannica L. total flavonoid macroporous resin orthogonal design |
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