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The activated hypothalamic magnocellular neurosecretory system and the one neuron -one neurohypophysial hormone concept
Authors:F. Vandesande  Prof.Dr. K. Dierickx
Affiliation:(1) Department of Embryology and Comparative Histology, Rijksuniversiteit, Gent, Belgium;(2) Laboratorium voor Embryologie en Vergelijkende Histologie, Godshuizenlaan, 4, B-9000 Rijksuniversiteit, Gent, Belgium
Abstract:Summary The activated hypothalamic magnocellular neurosecretory system of the rat was studied in tissue sections, double stained with the unlabeled antibody peroxidase-antiperoxidase complex (PAP) technique. The results indicate that in animals with an activated hypothalamic magnocellular neuroendocrine system, as well as in normal animals, vasopressin and oxytocin are exclusively synthesized in separate vasopressinergic and oxytocinergic neurons.This investigation was supported by a grant from the Belgian Nationaal Fonds voor Geneeskundig Wetenschappelijk Onderzoek
Keywords:Magnocellular neurosecretory system  Activation  Rat  Vasopressinergic neurons  Oxytocinergic neurons  Immunocytochemistry
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