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Indole-2-carboxamides as novel NR2B selective NMDA receptor antagonists |
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| Authors: | Borza István Kolok Sándor Gere Anikó Agai-Csongor Eva Agai Béla Tárkányi Gábor Horváth Csilla Barta-Szalai Gizella Bozó Eva Kiss Csilla Bielik Attila Nagy József Farkas Sándor Domány György |
| Affiliation: | Gedeon Richter Ltd., POB 27, H-1475 Budapest 10, Hungary. i.borza@richter.hu |
| Abstract: |  A novel series of indole-2-carboxamide derivatives was prepared and identified as NR2B selective NMDA receptor antagonists. The influence of the number and position of OH groups on the indole skeleton as well as the substitution of the piperidine ring on the biological activity of the compounds was studied. |
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