Abstract: | It was shown during experiments on unrestrained rats that rhythmic stimulation of the pyramidal tract produced a statistically significant increase in the functional activity of neuronal populations of the sensorimotor cortex, manifesting as potentiation of the primary, positive phase of pyramidal cortical response. Combined rhythmically matched stimulation of the pyramidal tract and of the lateral hypothalamus leads to statistically significant enhancement in potentiation of the positive phase of pyramidal cortical response compared with effects produced independently of hypothalamic involvement. When stimulation of the pyramidal tract and the lateral hypothalamus are combined with stimulation applied at the same periodicity to the sensorimotor cortex, a further statistically significant enhancement in potentiation of the positive phase of pyramidal cortical response is seen in addition to the potentiating effect produced by hypothalamic stimulation.Institute for Brain Research of the All-Union Scientific Center of Mental Health, Academy of Medical Sciences of the USSR, Moscow. Translated from Neirofiziologiya, Vol. 18, No. 3, pp. 367–373, May–June, 1986. |