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Synergistic actions of estrogen and androgen on the sexual behavior of the castrated male rabbit.
Authors:C Beyer  L de la Torre  K Larsson  G Pérez-Palacios
Affiliation:1. División de Ciencias Biológicas y de la Salud, Universidad Autónoma Metropolitana-Iztapalapa, México 13, D.F., Mexico;2. Departamento de Investigación Cientifica, Institute Mexicano del Seguro Social Mexico
Abstract:Daily injections of 2.5 mg dihydrotestosterone (DHT) for 30 days induced sexual behavior in 19% of piepuberally and 62% of postpuberally castrated New Zealand white male rabbits. Combined treatment of 2.5 mgm DHT plus 5 μgm of estradiol benzoate (EB) activated sexual behavior in 100 and 85% of prepuberally and postpuberally castrated rabbits respectively. Moreover, subjects (Ss) receiving DHT + EB displayed sexual activity in a significantly higher percentage of tests and presented a higher frequency of mounts and intromissions than those Ss receiving only DHT. The results demonstrate that estrogen synergizes with androgen (DHT) to stimulate sexual behavior in the male rabbit.
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