High activity of choline acetyltransferase induced in neuroblastoma X glia hybrid cells |
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Authors: | T. Amano B. Hamprecht W. Kemper |
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Affiliation: | 1. Department of Chemistry, Kerman Branch, Islamic Azad University, Kerman, Iran;2. Department of Chemistry, Shahid Bahonar University of Kerman, Kerman, Iran |
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Abstract: | ![]() Hybrids were made between rat glioma X mouse neuroblastoma cell lines and were examined for the specific activities of choline acetyltransferase and acetylcholinesterase. The specific activities of choline acetyltransferase of the hybrids were as high as those in normal brain, whereas neither parent line showed appreciable activities. The electrical excitability of the neuroblastoma cells was retained in the hybrids. |
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