The SiFi-CC project – Feasibility study of a scintillation-fiber-based Compton camera for proton therapy monitoring |
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| Institution: | 1. Physics Institute 3B, RWTH Aachen University, Aachen, Germany;2. Marian Smoluchowski Institute of Physics, Jagiellonian University, Kraków, Poland;1. INFN Sezione di Milano, Italy;2. Dipartimento di Fisica, Sapienza Università di Roma, Italy;3. INFN Sezione di Roma, Italy;4. INFN Sezione dei Laboratori di Frascati, Roma, Italy;5. Museo Storico della Fisica e Centro Studi e Ricerche “E. Fermi”, Roma, Italy;6. Dipartimento di Scienze di Base e Applicate per l’Ingegneria, Sapienza Università di Roma, Italy;7. INFN Sezione di Pisa, Italy;8. Dipartimento di Fisica, Università degli Studi di Milano, Italy;9. Scuola di Specializzazione in Fisica Medica, Sapienza Università di Roma, Roma, Italy;10. Dipartimento di Fisica “E. Fermi”, Università di Pisa, Pisa, Italy;1. Proton Therapy Center, National Cancer Center, Goyang, Republic of Korea;2. Department of Bio-Convergence Engineering, Korea University, Seoul, Republic of Korea;3. Department of Radiation Oncology, Samsung Medical Center, Seoul, Republic of Korea;1. Jožef Stefan Institute, Ljubljana, Slovenia;2. Memorial Sloan Kettering Cancer Center, New York, NY, USA;3. IFIC/CSIC, Valencia, Spain;4. University of Michigan, Ann Arbor, MI, USA;5. Ohio State University, Columbus, OH, USA;1. Department of Biomedical Engineering, University of California, Davis, CA 95616, USA;2. Institute of Medical Device and Imaging, College of Medicine, National Taiwan University, No.1, Sec. 1, Jen Ai Rd., Zhongzheng Dist., Taipei City 100, Taiwan;1. Department of Integrated Health Science, Nagoya University Graduate School of Medicine, Aichi, Japan;2. Department of Medical Technology, Nagoya University Hospital, Aichi, Japan;3. Takasaki Advanced Radiation Research Institute, Quantum Beam Science Research Directorate, National Institutes for Quantum Science and Technology (QST), Gunma, Japan;4. Department of Biomedical Engineering, University of California, Davis, USA;5. Department of Proton Therapy Physics, Nagoya Proton Therapy Center, Nagoya City University West Medical Center, Aichi, Japan;6. Faculty of Science and Engineering, Waseda University, Tokyo, Japan |
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| Abstract: | One of the big challenges for proton therapy is the development of tools for online monitoring of the beam range, which are suited to operate in clinical conditions and can be included in the clinical practice. A Compton camera based on stacks of heavy scintillating fibers used for prompt-gamma imaging is a promising approach for this task. It provides full, three-dimensional information on the deposited dose distribution while showing a high detection efficiency and rate capability due to its high granularity. The investigation of the rate capability and detection efficiency of such a camera under clinical conditions by means of Geant4 simulations is presented along with the event construction algorithm. The results hint towards a very low pile-up rate in the detector and a relatively high detection efficiency, so that imaging of a single proton beam spot appears to be an achievable goal. |
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| Keywords: | Proton therapy Prompt-gamma imaging Range verification Compton camera |
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