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神经起步点产生的一种新型簇放电节律———阵发周期1节律
引用本文:古华光,任维,杨明浩,陆启韶.神经起步点产生的一种新型簇放电节律———阵发周期1节律[J].生物物理学报,2002,18(4):440-447.
作者姓名:古华光  任维  杨明浩  陆启韶
作者单位:1. 航天医学工程研究所,北京,100094
2. 北京航空航天大学理学院,北京,100083
基金项目:科技部(2001CCA00700),国家自然科学基金(30270432)资助项目
摘    要:实验中发现了神经起步点产生的一种新型的簇放电节律--阵发周期1节律。其特征如下:连续周期1放电与休止期(quiescence)轮流出现;非周期性,连续放电持续期、连续放电次数以及休止期有较大变异性;位于周期1节律和静息状态之间。具有较长周期的伪单色噪声激励的FHN(FizHugh-Nagumo)模型可以产生类似的阵发周期1节律。模型和实验中的阵发周期1节律的统计特征、变化规律和所处的参数区间相类似。这表明:阵发周期1节律是由与伪单色噪声类似的长时程振荡激励引起的。

关 键 词:簇放电  阵发  自发放电  节律  动作电位间期  随机自共振
文章编号:1000-6737(2002)04-0440-08
修稿时间:2002年1月11日

A NOVEL BURSTING IN THE EXPERIMENTAL NEURONAL PACEMAKER, INTERMITTENT PERIOD 1 SPIKING
GU Hua-guang ,REN Wei ,YANG Ming-hao ,LU Qi-shao.A NOVEL BURSTING IN THE EXPERIMENTAL NEURONAL PACEMAKER, INTERMITTENT PERIOD 1 SPIKING[J].Acta Biophysica Sinica,2002,18(4):440-447.
Authors:GU Hua-guang  REN Wei  YANG Ming-hao  LU Qi-shao
Institution:GU Hua-guang 1,REN Wei 1,YANG Ming-hao 1,LU Qi-shao 2
Abstract:A novel bursting, intermittent period 1 spiking, was observed in the experimental neuronal pacemaker. It showed the characteristics as follows: First, its spike trains randomly transiting between continual period 1 spiking and intermittency. Second, the duration of the intermittency, the duration and the number of the continual period 1 spikes exhibited large variability, indicating that the firing pattern was not periodic. Last, it lay between period 1 spiking and at rest. Intermittent period 1 spiking similar to experiments was simulated in the FHN(FitzHugh-Nagumo) model driven by quasi-monochromatic noise (QMN) with a long basic period. The statistical character, the changing regularity and the parameter region of two intermittent period 1 spiking were similar. The results showed that the intermittent period 1 spiking might be induced by an oscillation similar to the QMN with a long basic period.
Keywords:Bursting  Intermittent  Spontaneous  discharge  Rhythm  Interspike  intervals  Autonomous  stochastic  resonance
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