Lysine and methionine overproduction by an Escherichia coli strain transformed with Pseudomonas acidovorans DNA |
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| Authors: | J. Alvarez-Jacobs D. Court G. Guarneros |
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| Affiliation: | (1) Departamento de Genética y Biologia Molecular, CINVESTAV, Apdo. Postal 14-740, 07000 México City, Mexico;(2) Frederick Cancer Research Facility, NCI, Frederick, MD, USA;(3) Present address: Coordinación de Investigación y Posgrado, Facultad de Estudios Superiores Cuautitlán, UNAM, Apdo. Postal 222, 54700 Cuautilán Izcalli Mex., Mexico |
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| Abstract: | ![]()
Summary An ethionine resistant, methionine-overproducingEscherichiacoli mutant was transformed with plasmids bearing DNA isolated from aPseudomonasacidovorans, lysine-overproducing strain, with a feedback-insensitive aspartokinase. The resulting transformants overproduced both lysine and methionine. |
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