间充质干细胞治疗炎症性肠病的应用及前景

炎症性肠病（IBD）是一种慢性非特异性肠道炎性疾病,其病因未明,有终生复发倾向,重症者迁延不愈。早期治疗以药物为主,部分重症患者后期需要手术干预。近年来,间充质干细胞（MSCs）由于具有多向分化潜能、免疫调节及组织修复功能已被广泛应用于IBD治疗的临床前基础研究中,具有一定理论基础。在已开展的MSCs治疗IBD的临床试验中,尚未有严重并发症的报道。虽然目前MSCs治疗不是IBD的标准治疗方案,但今后可能会成为一种新的治疗选择,特别是对于难治性或合并肛瘘的IBD患者。本文就MSCs的概况及其在IBD治疗的作用机制和应用前景作一综述。     

抗菌肽的作用机制、生物活性及应用研究进展

抗菌肽广泛存在于生物界,是辅助生物机体抵抗外来病原体入侵的重要防御分子。抗菌肽不仅能抑制、杀灭多种细菌,而且具有抗真菌、抗寄生虫、抗病毒、抗肿瘤和免疫调节等生物学活性。抗菌肽的作用机制与传统抗生素不同,不仅具有广谱抗微生物作用,而且不易诱导机体产生耐药性,因此,在治疗临床耐药菌株方面具有极大的开发潜力。     

上海辰山植物园植物收集的现状和展望

上海辰山植物园于2005年开始筹建,与此同时启动了的植物收集工作。本文就辰山植物园基本情况、植物收集中长远规划、进展及技术策略进行了论述。活植物收集和标本收集是辰山植物园植物收集工作的两个方面。活植物收集包括以华东植物区系植物为主的物种收集和以上海适生的观赏植物为主的园艺品种收集,如鸢尾属、绣球属、荚蓬属、锦带属和绣线菊属的舭赏园艺品种。截止到2010年,辰山植物园共收集了9000种和园艺品种。其中,华东植物区系物种有1700种,来自世界范围专业苗圃的园艺品种有2800个,另有4500种和品种是种植于温室的热带和亚热带植物。目前共收集了近10000份标本,多数为研究和活植物收集的凭证标本,全部存放于上海辰山植物园标本馆（CSH）。     

上海辰山植物园植物收集的现状和展望

上海辰山植物园于2005年开始筹建,与此同时启动了的植物收集工作。本文就辰山植物园基本情况、植物收集中长远规划、进展及技术策略进行了论述。活植物收集和标本收集是辰山植物园植物收集工作的两个方面。活植物收集包括以华东植物区系植物为主的物种收集和以上海适生的观赏植物为主的园艺品种收集,如鸢尾属、绣球属、荚蒾属、锦带属和绣线菊属的观赏园艺品种。截止到2010年,辰山植物园共收集了9000种和园艺品种。其中,华东植物区系物种有1700种,来自世界范围专业苗圃的园艺品种有2800个,另有4500种和品种是种植于温室的热带和亚热带植物。目前共收集了近10000份标本,多数为研究和活植物收集的凭证标本,全部存放于上海辰山植物园标本馆（CSH）。     

Basil polysaccharides: A review on extraction,bioactivities and pharmacological applications

Traditional Chinese Medicine has been widely used in China and is regarded as the most commonly used treatment. As a natural plant used in traditional Chinese Medicine, Basil has various functions associated with a number of its components. There are many compositions in basil including polysaccharides, naphtha, steroids, flavone, coumarins, vitamins, and so on. Among these, polysaccharides play a significant role in based therapeutics. The article summarizes that basil polysaccharides have a lot of biological activities and pharmacological applications, such as their antitumor activity, antioxidant activity, anti-aging activity, immunity enhancement effect, hypolipidemic and anti-atherosclerotic effects, antibacterial effect, treatment of diabetes mellitus, and so on. This review summarized the extraction method, purification method, compositions, pharmacological applications, molecular weight, biological activities, and prospects of basil polysaccharides, providing a basis for further study of basil and basil polysaccharides.     

植物空间诱变育种的现状与展望

本文在简要回顾植物空间诱变育种历史的基础上,论述了植物空间诱变育种的机理,植物在高真空、微重力、强辐射、交变磁场及其他因素的综合作用下产生变异和植物空间诱变育种效应以及突变性状的遗传;全面综述了空间诱变育种在中国作物新品种、特异优良种质材料的创新中取得的成就.最后对未来植物空间诱变育种的应用前景进行了展望,并指出空间诱变技术开创了植物育种的又一新途径.     

曲江县养牛业及其发展前景

着重就曲江县养牛业的发展历史、现状、规模及其所取得的经济效益、生态效益和社会效益进行了总结．阐述了曲江县发展养牛业的有利条件．     

Mesenchymal stem cell-derived small extracellular vesicles in the treatment of human diseases:Progress and prospect

Mesenchymal stem cells(MSCs)are self-renewing,multipotent cells that could differentiate into multiple tissues.MSC-based therapy has become an attractive and promising strategy for treating human diseases through immune regulation and tissue repair.However,accumulating data have indicated that MSC-based therapeutic effects are mainly attributed to the properties of the MSC-sourced secretome,especially small extracellular vesicles(sEVs).sEVs are signaling vehicles in intercellular communication in normal or pathological conditions.sEVs contain natural contents,such as proteins,mRNA,and microRNAs,and transfer these functional contents to adjacent cells or distant cells through the circulatory system.MSC-sEVs have drawn much attention as attractive agents for treating multiple diseases.The properties of MSC-sEVs include stability in circulation,good biocompatibility,and low toxicity and immunogenicity.Moreover,emerging evidence has shown that MSC-sEVs have equal or even better treatment efficacies than MSCs in many kinds of disease.This review summarizes the current research efforts on the use of MSC-sEVs in the treatment of human diseases and the existing challenges in their application from lab to clinical practice that need to be considered.