HPTLC determination of vasicine and vasicinone in Adhatoda vasica

A simple high-performance thin-layer chromatographic (HPTLC) method has been developed for the simultaneous determination of the pharmacologically important quinazoline alkaloids vasicine and vasicinone in Adhatoda vasica. The assay combines the separation and quantification of the analytes on silica gel 60 GF254 HPTLC plates with visualisation under UV and scanning at 270 and 281 nm. Using this technique, the alkaloidal content of different parts of the title plant have been determined.     

Vasicol,a new alkaloid from Adhatoda vasica

A novel alkaloid isolated from the roots of Adhatoda vasica has been characterized as 1,2,3,4,9,11 hexahydro pyrrolo (2,1-b) quinazolin-3,11 diol by chemical and spectroscopic methods. Vasicinone has also been isolated from the roots of this plant.