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1.
The incidence of vomiting before the administration of analgesics was studied in 109 patients admitted to hospital as emergencies with prolonged ischaemic cardiac pain. In transmural myocardial infarction (58 patients) the incidence was 43% (anterior infarction 58%, inferior infarction 41%). Of the 23 patients with myocardial necrosis but without transmural infarction (that is, those with diffuse or subendocardial necrosis) and the 28 with coronary insufficiency but no necrosis, only one patient in each group experienced vomiting. When vomiting occurs early in association with cardiac pain transmural infarction may be expected in 90% of patients. 相似文献
2.
Lisa Clayton Christopher Hiley Simon Davies Richard D'souza Peter Jones Richard Strange Geoffrey Aber 《Free radical research》1992,17(4):271-278
The sensitivity of isolated glomeruli from normotensive (Wistar-Kyoto, WKY) and spontaneously hypertensive (SHR) strains to oxidant stress was studied by determining the incidence of pyknosis, karyohexis and karyolysis after incubation with different concentrations of hydrogen peroxide (H2O2) (4.7 × 10-9-10-3 M). Even though the proportion of glomeruli containing nuclei that demonstrated these features increased progressively with increasing concentrations of H2O2, the number of severely damaged glomeruli was relatively small even at concentrations of 4.7 × 10-3 M.
Examination of the surface epithelial cells of glomeruli using scanning electron microscopy revealed no evidence of disturbance of the macroscopic or podocyte structure or, of increased blebbing after H2O2-treatment. These data suggest damage to nuclei is an early result of ROS stress on glomeruli.
Preincubation of WKY glomeruli with captopril or lisinopril resulted in a significant drop in the proportion of WKY glomeruli demonstrating structural damage after oxidant stress. In contrast, preincubation of SHR glomeruli with lisinopril had no effect on oxidant-induced changes in the morphology of SHR glomeruli, whereas captopril effected a significant increase in the proportion of glomeruli demonstrating damage at all concentrations of H2O2. 相似文献
Examination of the surface epithelial cells of glomeruli using scanning electron microscopy revealed no evidence of disturbance of the macroscopic or podocyte structure or, of increased blebbing after H2O2-treatment. These data suggest damage to nuclei is an early result of ROS stress on glomeruli.
Preincubation of WKY glomeruli with captopril or lisinopril resulted in a significant drop in the proportion of WKY glomeruli demonstrating structural damage after oxidant stress. In contrast, preincubation of SHR glomeruli with lisinopril had no effect on oxidant-induced changes in the morphology of SHR glomeruli, whereas captopril effected a significant increase in the proportion of glomeruli demonstrating damage at all concentrations of H2O2. 相似文献
3.
4.
The Biogeochemistry of Carbon at Hubbard Brook 总被引:6,自引:1,他引:5
T. J. Fahey T. G. Siccama C. T. Driscoll G. E. Likens J. Campbell C. E. Johnson J. J. Battles J. D. Aber J. J. Cole M. C. Fisk P. M. Groffman S. P. Hamburg R. T. Holmes P. A. Schwarz R. D. Yanai 《Biogeochemistry》2005,75(1):109-176
The biogeochemical behavior of carbon in the forested watersheds of the Hubbard Brook Experimental Forest (HBEF) was analyzed
in long-term studies. The largest pools of C in the reference watershed (W6) reside in mineral soil organic matter (43% of
total ecosystem C) and living biomass (40.5%), with the remainder in surface detritus (14.5%). Repeated sampling indicated
that none of these pools was changing significantly in the late-1990s, although high spatial variability precluded the detection
of small changes in the soil organic matter pools, which are large; hence, net ecosystem productivity (NEP) in this 2nd growth
forest was near zero (± about 20 g C/m2-yr) and probably similar in magnitude to fluvial export of organic C. Aboveground net primary productivity (ANPP) of the
forest declined by 24% between the late-1950s (462 g C/m2-yr) and the late-1990s (354 g C/m2-yr), illustrating age-related decline in forest NPP, effects of multiple stresses and unusual tree mortality, or both. Application
of the simulation model PnET-II predicted 14% higher ANPP than was observed for 1996–1997, probably reflecting some unknown
stresses. Fine litterfall flux (171 g C/m2-yr) has not changed much since the late-1960s. Because of high annual variation, C flux in woody litterfall (including tree
mortality) was not tightly constrained but averaged about 90 g C/m2-yr. Carbon flux to soil organic matter in root turnover (128 g C/m2-yr) was only about half as large as aboveground detritus. Balancing the soil C budget requires that large amounts of C (80 g C/m2-yr) were transported from roots to rhizosphere carbon flux. Total soil respiration (TSR) ranged from 540 to 800 g C/m2-yr across eight stands and decreased with increasing elevation within the northern hardwood forest near W6. The watershed-wide
TSR was estimated as 660 g C/m2-yr. Empirical measurements indicated that 58% of TSR occurred in the surface organic horizons and that root respiration comprised
about 40% of TSR, most of the rest being microbial. Carbon flux directly associated with other heterotrophs in the HBEF was
minor; for example, we estimated respiration of soil microarthropods, rodents, birds and moose at about 3, 5, 1 and 0.8 g C/m2-yr, respectively, or in total less than 2% of NPP. Hence, the effects of other heterotrophs on C flux were primarily indirect,
with the exception of occasional irruptions of folivorous insects. Hydrologic fluxes of C were significant in the watershed
C budget, especially in comparison with NEP. Although atmospheric inputs (1.7 g C/m2-yr) and streamflow outputs (2.7 g C/m2-yr) were small, larger quantities of C were transported within the ecosystem and a more substantial fraction of dissolved
C was transported from the soil as inorganic C and evaded from the stream as CO2 (4.0 g C/m2-yr). Carbon pools and fluxes change rapidly in response to catastrophic disturbances such as forest harvest or major windthrow
events. These changes are dominated by living vegetation and dead wood pools, including roots. If biomass removal does not
accompany large-scale disturbance, the ecosystem is a large net source of C to the atmosphere (500–1200 g C/m2-yr) for about a decade following disturbance and becomes a net sink about 15–20 years after disturbance; it remains a net
sink of about 200–300 g C/m2-yr for about 40 years before rapidly approaching steady state. Shifts in NPP and NEP associated with common small-scale or
diffuse forest disturbances (e.g., forest declines, pathogen irruptions, ice storms) are brief and much less dramatic. Spatial
and temporal patterns in C pools and fluxes in the mature forest at the HBEF reflect variation in environmental factors. Temperature
and growing-season length undoubtedly constrain C fluxes at the HBEF; however, temperature effects on leaf respiration may
largely offset the effects of growing season length on photosynthesis. Occasional severe droughts also affect C flux by reducing
both photosynthesis and soil respiration. In younger stands nutrient availability strongly limits NPP, but the role of soil
nutrient availability in limiting C flux in the mature forest is not known. A portion of the elevational variation of ANPP
within the HBEF probably is associated with soil resource limitation; moreover, sites on more fertile soils exhibit 20–25%
higher biomass and ANPP than the forest-wide average. Several prominent biotic influences on C pools and fluxes also are clear.
Biomass and NPP of both the young and mature forest depend upon tree species composition as well as environment. Similarly,
litter decay differs among tree species and forest types, and forest floor C accumulation is twice as great in the spruce–fir–birch
forests at higher elevations than in the northern hardwood forests, partly because of inherently slow litter decay and partly
because of cold temperatures. This contributes to spatial patterns in soil solution and streamwater dissolved organic carbon
across the Hubbard Brook Valley. Wood decay varies markedly both among species and within species because of biochemical differences
and probably differences in the decay fungi colonizing wood. Although C biogeochemistry at the HBEF is representative of mountainous
terrain in the region, other sites will depart from the patterns described at the HBEF, due to differences in site history,
especially agricultural use and fires during earlier logging periods. Our understanding of the C cycle in northern hardwood
forests is most limited in the area of soil pool size changes, woody litter deposition and rhizosphere C flux processes. 相似文献
5.
Reconciling Carbon-cycle Concepts, Terminology, and Methods 总被引:5,自引:1,他引:4
F. S. Chapin III G. M. Woodwell J. T. Randerson E. B. Rastetter G. M. Lovett D. D. Baldocchi D. A. Clark M. E. Harmon D. S. Schimel R. Valentini C. Wirth J. D. Aber J. J. Cole M. L. Goulden J. W. Harden M. Heimann R. W. Howarth P. A. Matson A. D. McGuire J. M. Melillo H. A. Mooney J. C. Neff R. A. Houghton M. L. Pace M. G. Ryan S. W. Running O. E. Sala W. H. Schlesinger E.-D. Schulze 《Ecosystems》2006,9(7):1041-1050
Recent projections of climatic change have focused a great deal of scientific and public attention on patterns of carbon (C)
cycling as well as its controls, particularly the factors that determine whether an ecosystem is a net source or sink of atmospheric
carbon dioxide (CO2). Net ecosystem production (NEP), a central concept in C-cycling research, has been used by scientists to represent two different
concepts. We propose that NEP be restricted to just one of its two original definitions—the imbalance between gross primary
production (GPP) and ecosystem respiration (ER). We further propose that a new term—net ecosystem carbon balance (NECB)—be
applied to the net rate of C accumulation in (or loss from [negative sign]) ecosystems. Net ecosystem carbon balance differs
from NEP when C fluxes other than C fixation and respiration occur, or when inorganic C enters or leaves in dissolved form.
These fluxes include the leaching loss or lateral transfer of C from the ecosystem; the emission of volatile organic C, methane,
and carbon monoxide; and the release of soot and CO2 from fire. Carbon fluxes in addition to NEP are particularly important determinants of NECB over long time scales. However,
even over short time scales, they are important in ecosystems such as streams, estuaries, wetlands, and cities. Recent technological
advances have led to a diversity of approaches to the measurement of C fluxes at different temporal and spatial scales. These
approaches frequently capture different components of NEP or NECB and can therefore be compared across scales only by carefully
specifying the fluxes included in the measurements. By explicitly identifying the fluxes that comprise NECB and other components
of the C cycle, such as net ecosystem exchange (NEE) and net biome production (NBP), we can provide a less ambiguous framework
for understanding and communicating recent changes in the global C cycle. 相似文献
6.
Robert M. Inman Mark L. Packila Kristine H. Inman Anthony J. Mccue Gary C. White Jens Persson Bryan C. Aber Mark L. Orme Kurt L. Alt Steven L. Cain Jay A. Fredrick Bob J. Oakleaf Shawn S. Sartorius 《The Journal of wildlife management》2012,76(4):778-792
Wolverines (Gulo gulo) in the conterminous United States have experienced range contraction, are uncommon, and have been designated as warranted for protection under the United States Endangered Species Act. Data from the southern edge of the wolverine's circumpolar distribution is sparse, and development of effective conservation strategies would benefit from a more complete understanding of the species' ecology. We captured and radio-monitored 30 wolverines in the Greater Yellowstone Ecosystem (GYE), tested for seasonal habitat selection by elevation band, and examined a suite of spatial characteristics to clarify our understanding of the wolverine's niche. Wolverines in GYE selected for areas >2,600 m latitude-adjusted elevation (LAE; n = 2,257 wolverine locations [12 F, 6 M]). Wolverines avoided areas <2,150 m LAE, including during winter when the vast majority of ungulates are pushed to these elevations by deep snow. Wolverine home ranges were large relative to body size, averaging 303 km2 for adult females and 797 km2 for adult males (n = 13 [8 F, 5 M] and 33 wolverine-years). Resident adults fit with Global Positioning System (GPS) collars used an area >75% the size of their multi-year home range in an average of 32 days (n = 7 [5 F, 2 M]). Average movement rates of 1.3 km/2-hr indicated that both sexes move distances equivalent to the diameter of their home range every 2 days or the circumference of their home range in <1 week (n = 1,329 2-hr movements, n = 12 individuals [7 F, 5 M]). This capability for movement, the short time-frame over which home ranges were developed, and a lack of home range overlap by same sex adults ( , 90% CI = 0.0–4.8%, n = 22 pairs) suggested territoriality. We estimated wolverine density to be 3.5/1,000 km2 of area >2,150 m LAE (95% CI = 2.8–9.6). Dispersal movements extended to at least 170 km for both sexes (n = 5 F, 2 M). At the southern edge of distribution, where suitable and unsuitable conditions exist in close proximity, wolverines selected high-elevation areas near alpine tree-line where a mix of forest, meadow, and boulder fields were present, deep snow-cover existed during winter, and low temperatures near freezing can occur throughout the year. Persistence in these areas where the growing season is brief requires large home ranges that are regularly patrolled, a social system that provides exclusive access to resources, and low densities. These characteristics, along with low reproductive rates, are prevalent throughout the species range, indicating that wolverines are specialists at exploiting a cold, unproductive niche where interspecific competition is limited. The vulnerability inherent in occupying this unproductive niche was likely influential in previous declines within the conterminous United States and will remain a factor as wolverines encounter modern human influences. Conserving wolverines in the conterminous United States will require collaborative management over a large geographic scale. © 2011 The Wildlife Society. 相似文献
7.
Net ecosystem productivity (NEP), net primary productivity (NPP), and water vapour exchange of a mature Pinus ponderosa forest (44°30′ N, 121°37′ W) growing in a region subject to summer drought were investigated along with canopy assimilation and respiratory fluxes. This paper describes seasonal and annual variation in these factors, and the evaluation of two generalized models of carbon and water balance (PnET‐II and 3‐PG) with a combination of traditional measurements of NPP, respiration and water stress, and eddy covariance measurements of above‐and below‐canopy CO2 and water vapour exchange. The objective was to evaluate the models using two years of traditional and eddy covariance measurements, and to use the models to help interpret the relative importance of processes controlling carbon and water vapour exchange in a water‐limited pine ecosystem throughout the year. PnET‐II is a monthly time‐step model that is driven by nitrogen availability through foliar N concentration, and 3‐PG is a monthly time‐step quantum‐efficiency model constrained by extreme temperatures, drought, and vapour pressure deficits. Both models require few parameters and have the potential to be applied at the watershed to regional scale. There was 2/3 less rainfall in 1997 than in 1996, providing a challenge to modelling the water balance, and consequently the carbon balance, when driving the models with the two years of climate data, sequentially. Soil fertility was not a key factor in modelling processes at this site because other environmental factors limited photosynthesis and restricted projected leaf area index to ~1.6. Seasonally, GEP and LE were overestimated in early summer and underestimated through the rest of the year. The model predictions of annual GEP, NEP and water vapour exchange were within 1–39% of flux measurements, with greater disparity in 1997 because soil water never fully recharged. The results suggest that generalized models can provide insights to constraints on productivity on an annual basis, using a minimum of site data. 相似文献
8.
Gareth Williams Jaswinder S Gill Vic Aber Hugh M Mather 《BMJ (Clinical research ed.)》1988,296(6617):233-235
Vibration perception threshold was measured with a biothesiometer by a single observer at both medial malleoli and both big toes in 110 diabetic patients aged 15-65 selected at random and in 64 non-diabetic subjects aged 20-65. The vibration perception threshold showed appreciable individual variation both between contralateral sites and between ipsilateral sites, differing by at least 30% between the big toes in 26 (24%) of the diabetic patients and 16 (25%) of the non-diabetic group. Variability between sites was significantly greater in the diabetics than the normal subjects. The vibration perception threshold exceeded published normal values at one or more sites in 22 of the diabetic patients but at all four sites in only four.The wide variability in vibration perception threshold among sites may be due to the tissue characteristics locally and, in diabetic patients, possibly to asymmetric neuropathy. Biothesiometer readings at single or unilateral sites may be unrepresentative or misleading. 相似文献
9.
Primary production and nitrogen allocation of field grown sugar maples in relation to nitrogen availability 总被引:2,自引:1,他引:1
Above ground net primary production (NPP), nitrogen (N) allocation, and retranslocation from senescing leaves were measured in 7 sugar-maple dominated sites having annual net N mineralization rates ranging from 26 to 94 kg · ha–1 · yr–1. The following responses were observed: (1) Green sun leaves on richer sites had higher N mass per unit leaf area than sun leaves on poorer sites; (2) Total canopy N varied much less than annual net mineralization, ranging from 81 to 111 kg · ha–1; (3) This was due to the existence of a large and relatively constant pool of N which was retranslocated from senescing leaves for use the following year (54 to 80 kg · ha–1); (4) The percentage of canopy N retranslocated by sugar maple was also relatively constant, but was slightly higher on the richer sites. Percent N in leaf litter did not change across the gradient; (5) Above ground NPP increased linearly in relation to N allocated above ground. Therefore, N use efficiency, expressed as above ground NPP divided by N allocated above ground was constant; (6) N use efficiency expressed as (NPP above ground/total N availability) was a curvilinear function of N availability; and (7) This pattern reflected a decreasing apparent allocation of N below ground with decreasing N availability. 相似文献
10.
Fine root turnover in forest ecosystems in relation to quantity and form of nitrogen availability: a comparison of two methods 总被引:20,自引:0,他引:20
John D. Aber Jerry M. Melillo Knute J. Nadelhoffer Charles A. McClaugherty John Pastor 《Oecologia》1985,66(3):317-321
Summary Two methods of estimating fine root production and turnover are compared for 13 forest ecosystems exhibiting a wide range in form (NH4
+ vs. NO3
-) and quantity of available nitrogen. The two methods are by comparison of seasonal maxima and minima in biomess and by nitrogen budgeting. Both methods give similar results for stands with low rates of nitrification. The budgeting method predicts higher fine root turnover and productivity than the max-min method for systems with significant rates of nitrification. 相似文献