全文获取类型
收费全文 | 60198篇 |
免费 | 5464篇 |
国内免费 | 5774篇 |
出版年
2024年 | 27篇 |
2023年 | 810篇 |
2022年 | 990篇 |
2021年 | 3050篇 |
2020年 | 2325篇 |
2019年 | 2935篇 |
2018年 | 2812篇 |
2017年 | 1972篇 |
2016年 | 2752篇 |
2015年 | 3944篇 |
2014年 | 4757篇 |
2013年 | 4994篇 |
2012年 | 5859篇 |
2011年 | 5311篇 |
2010年 | 3280篇 |
2009年 | 2991篇 |
2008年 | 3353篇 |
2007年 | 3058篇 |
2006年 | 2513篇 |
2005年 | 2069篇 |
2004年 | 1695篇 |
2003年 | 1501篇 |
2002年 | 1249篇 |
2001年 | 959篇 |
2000年 | 911篇 |
1999年 | 845篇 |
1998年 | 544篇 |
1997年 | 505篇 |
1996年 | 492篇 |
1995年 | 414篇 |
1994年 | 420篇 |
1993年 | 278篇 |
1992年 | 365篇 |
1991年 | 298篇 |
1990年 | 241篇 |
1989年 | 186篇 |
1988年 | 147篇 |
1987年 | 116篇 |
1986年 | 82篇 |
1985年 | 95篇 |
1984年 | 50篇 |
1983年 | 58篇 |
1982年 | 43篇 |
1981年 | 26篇 |
1980年 | 15篇 |
1979年 | 17篇 |
1978年 | 9篇 |
1976年 | 10篇 |
1975年 | 9篇 |
1965年 | 10篇 |
排序方式: 共有10000条查询结果,搜索用时 31 毫秒
1.
2.
Fluid-structural coupling occurs when microcantilever sensors vibrate in a fluid. Due to the complexity of the mechanical characteristics of microcantilevers and lack of high-precision microscopic mechanical testing instruments, effective methods for studying the fluid-structural coupling of microcantilevers are lacking, especially for non-rectangular microcantilevers. Here, we report fluid-structure interactions (FSI) of the cable-membrane structure via a macroscopic study. The simplified aeroelastic model was introduced into the microscopic field to establish a fluid-structure coupling vibration model for microcantilever sensors. We used the finite element method to solve the coupled FSI system. Based on the simplified aeroelastic model, simulation analysis of the effects of the air environment on the vibration of the commonly used rectangular microcantilever was also performed. The obtained results are consistent with the literature. The proposed model can also be applied to the auxiliary design of rectangular and non-rectangular sensors used in fluid environments. 相似文献
3.
Xiaobin Chen Hugo Giambini Ephraim Ben-Abraham Kai-Nan An Ahmad Nassr Chunfeng Zhao 《PloS one》2015,10(10)
IntroductionAn increased bone mineral density (BMD) in the proximity to tendon insertion can improve rotator cuff repair and healing. However, how a decrease of BMD in the humeral head affects the biomechanical properties of the rotator cuff tendon is still unclear. Previous studies have demonstrated ovariectomy in animals to lead to osteoporosis and decreased BMD, and Teriparatide (PTH) administration to improve BMD and strength of bone. This study aimed to explore the correlation between humeral head BMD and infraspinatus (ISP) tendon insertion strength, and if an increase in bone quantity of the humeral head can improve the strength of the rotator cuff.ResultsSignificant differences were observed in the measured humeral head BMD of the Control and OVX-PTH groups compared to the OVX-Saline group (P = 0.0004 and P = 0.0024, respectively). No significant difference was found in failure stress among the three groups, but an expected trend with the control group and OVX-PTH group presenting higher failure strength compared to the OVX-Saline group. BMD at the humeral head showed a positive linear correlation with stress (r2 = 0.54). Histology results showed the superiority in OVX-PTH group ISP enthesis compared to the OVX-Saline group.ConclusionBone loss of the humeral head leads to decreased tendon/bone insertion strength of the infraspinatus tendon enthesis. Teriparatide administration can increase bone density of the humeral head and may improve the mechanical properties of the infraspinatus tendon enthesis. 相似文献
4.
5.
Feng Xue Zhoushan Wu Jinrong Tong Jialun Zheng 《Bioscience, biotechnology, and biochemistry》2017,81(10):1891-1898
This study investigated the effects of high-intensity ultrasound and glycosylation on the structural and interfacial properties of the Maillard reaction conjugates of buckwheat protein isolate (BPI). The covalent attachment of dextran to BPI was confirmed by examination of the Fourier-transform infrared spectra. Emulsifying properties of the conjugates obtained by ultrasound treatment were improved as compared to those obtained by classical heating. Structural feature analyses suggested that conjugates obtained by ultrasound treatment had less α-helix and more random coil, higher surface hydrophobicity and less compact tertiary structure as compared to those obtained by classical heating. The surface activity measurement revealed that the BPI–dextran conjugates obtained by ultrasound treatment were closely packed and that each molecule occupied a small area of the interface. Combination of ultrasonic treatment and glycosylation was proved to be an efficient way to develop new stabilizers and thickening agents for food in this study. 相似文献
6.
One new genus of the spider subfamily Coelotinae, Flexicoelotes
gen. n., with five new species is described from southern China: Flexicoelotes
huyunensis
sp. n. (female), Flexicoelotes
jiaohanyanensis
sp. n. (male and female), Flexicoelotes
jinlongyanensis
sp. n. (male and female), Flexicoelotes
pingzhaiensis
sp. n. (female), Flexicoelotes
xingwangensis
sp. n. (male and female). 相似文献
7.
8.
9.
Bin Zhu Chongwen Yang Hongrong Liu Lingpeng Cheng Feng Song Songjun Zeng Xiaojun Huang Gang Ji Ping Zhu 《Journal of molecular biology》2014
Many double-stranded RNA (dsRNA) viruses are capable of transcribing and capping RNA within a stable icosahedral viral capsid. The turret of turreted dsRNA viruses belonging to the family Reoviridae is formed by five copies of the turret protein, which contains domains with both 7-N-methyltransferase and 2′-O-methyltransferase activities, and serves to catalyze the methylation reactions during RNA capping. Cypovirus of the family Reoviridae provides a good model system for studying the methylation reactions in dsRNA viruses. Here, we present the structure of a transcribing cypovirus to a resolution of ~ 3.8 Å by cryo-electron microscopy. The binding sites for both S-adenosyl-l-methionine and RNA in the two methyltransferases of the turret were identified. Structural analysis of the turret in complex with RNA revealed a pathway through which the RNA molecule reaches the active sites of the two methyltransferases before it is released into the cytoplasm. The pathway shows that RNA capping reactions occur in the active sites of different turret protein monomers, suggesting that RNA capping requires concerted efforts by at least three turret protein monomers. Thus, the turret structure provides novel insights into the precise mechanisms of RNA methylation. 相似文献
10.
Mapping QTLs and meta-QTLs for two inflorescence architecture traits in multiple maize populations under different watering environments 总被引:1,自引:0,他引:1
Xiaoqiang Zhao Yunling Peng Jinwen Zhang Peng Fang Boyang Wu 《Molecular breeding : new strategies in plant improvement》2017,37(7):91
Drought significantly affects the architectural development of maize inflorescence, which leads to massive losses in grain yield. However, the genetic mechanism for traits involved in inflorescence architecture in different watering environments, remains poorly understood in maize. In this study, 19 QTLs for tassel primary branch number (TBN) and ear number per plant (EN) were detected in 2 F2:3 populations under both well-watered and water-stressed environments by single environment mapping with composite interval mapping (CIM); 11/19 QTLs were detected under water-stressed environments. Moreover, 21 QTLs were identified in the 2 F2:3 populations by joint analysis of all environments with a mixed linear model based on composite interval mapping (MCIM), 11 QTLs were involved in QTL × environment interactions, seven epistatic interactions were identified with additive by additive/dominance effects. Remarkably, 12 stable QTLs (sQTLs) were simultaneously detected by single environment mapping with CIM and joint analysis through MCIM, which were concentrated in ten bins across the chromosomes: 1.05_1.07, 1.08_1.10, 2.01_2.04, 3.01, 4.06, 4.09, 5.06_5.07, 6.05, 7.00, and 7.04 regions. Twenty meta-QTLs (mQTLs) were detected across 19 populations under 51 watering environments using a meta-analysis, and 34 candidate genes were predicted in corresponding mQTLs regions to be involved in the regulation of inflorescence development and drought resistance. Therefore, these results provide valuable information for finding quantitative trait genes and to reveal the genetic mechanisms responsible for TBN and EN under different watering environments. Furthermore, alleles for TBN and EN provide useful targets for marker-assisted selection to generate high-yielding maize varieties. 相似文献