全文获取类型
收费全文 | 2034篇 |
免费 | 207篇 |
出版年
2024年 | 1篇 |
2023年 | 12篇 |
2022年 | 7篇 |
2021年 | 42篇 |
2020年 | 37篇 |
2019年 | 31篇 |
2018年 | 44篇 |
2017年 | 46篇 |
2016年 | 80篇 |
2015年 | 110篇 |
2014年 | 148篇 |
2013年 | 144篇 |
2012年 | 168篇 |
2011年 | 163篇 |
2010年 | 129篇 |
2009年 | 128篇 |
2008年 | 153篇 |
2007年 | 128篇 |
2006年 | 133篇 |
2005年 | 107篇 |
2004年 | 119篇 |
2003年 | 97篇 |
2002年 | 86篇 |
2001年 | 16篇 |
2000年 | 4篇 |
1999年 | 10篇 |
1998年 | 11篇 |
1997年 | 4篇 |
1996年 | 6篇 |
1995年 | 6篇 |
1994年 | 13篇 |
1993年 | 6篇 |
1992年 | 19篇 |
1991年 | 5篇 |
1990年 | 5篇 |
1989年 | 2篇 |
1988年 | 1篇 |
1986年 | 1篇 |
1985年 | 1篇 |
1984年 | 3篇 |
1983年 | 4篇 |
1982年 | 4篇 |
1981年 | 1篇 |
1979年 | 1篇 |
1976年 | 1篇 |
1975年 | 1篇 |
1974年 | 1篇 |
1972年 | 1篇 |
1958年 | 1篇 |
排序方式: 共有2241条查询结果,搜索用时 62 毫秒
1.
François Blanquart Sylvain Gandon 《Evolution; international journal of organic evolution》2014,68(6):1617-1628
Populations often experience variable conditions, both in time and space. Here we develop a novel theoretical framework to study the evolution of migration under the influence of spatially and temporally variable selection and genetic drift. First, we examine when polymorphism is maintained at a locus under heterogeneous selection, as a function of the pattern of spatial heterogeneity and the migration rate. In a second step, we study how levels of migration evolve under the joint action of kin competition and local adaptation at a polymorphic locus. This analysis reveals the existence of evolutionary bistability, whereby a low or a high migration rate may evolve depending on the initial conditions. Last, we relax several assumptions regarding selection heterogeneity commonly made in previous studies and explore the consequences of more complex spatial and temporal patterns of variability in selection on the evolution of migration. We found that small modifications in the pattern of environmental heterogeneity may have dramatic effects on the evolution of migration. This work highlights the importance of considering more general scenarios of environmental heterogeneity when studying the evolution of life‐history traits in ecologically complex settings. 相似文献
2.
Clotilde Lepers Mathilde Dufay Sylvain Billiard 《Evolution; international journal of organic evolution》2014,68(12):3581-3598
The mode of pollination is often neglected regarding the evolution of selfing. Yet the distribution of mating systems seems to depend on the mode of pollination, and pollinators are likely to interfere with selfing evolution, since they can cause strong selective pressures on floral traits. Most selfing species reduce their investment in reproduction, and display smaller flowers, with less nectar and scents (referred to as selfing syndrome). We model the evolution of prior selfing when it affects both the demography of plants and pollinators and the investment of plants in pollination. Including the selfing syndrome in the model allows to predict several outcomes: plants can evolve either toward complete outcrossing, complete selfing, or to a stable mixed‐mating system, even when inbreeding depression is high. We predict that the evolution to high prior selfing could lead to evolutionary suicides, highlighting the importance of merging demography and evolution in models. The consequence of the selfing syndrome on plant–pollinator interactions could be a widespread mechanism driving the evolution of selfing in animal‐pollinated taxa. 相似文献
3.
4.
5.
6.
Franck Debeurme Antoine Picciocchi Marie-Claire Dagher Didier Grunwald Sylvain Beaumel Franck Fieschi Marie-José Stasia 《The Journal of biological chemistry》2010,285(43):33197-33208
The X+-linked chronic granulomatous disease (X+-CGD) variants are natural mutants characterized by defective NADPH oxidase activity but with normal Nox2 expression. According to the three-dimensional model of the cytosolic Nox2 domain, most of the X+-CGD mutations are located in/or close to the FAD/NADPH binding regions. A structure/function study of this domain was conducted in X+-CGD PLB-985 cells exactly mimicking 10 human variants: T341K, C369R, G408E, G408R, P415H, P415L, Δ507QKT509-HIWAinsert, C537R, L546P, and E568K. Diaphorase activity is defective in all these mutants. NADPH oxidase assembly is normal for P415H/P415L and T341K mutants where mutation occurs in the consensus sequences of NADPH- and FAD-binding sites, respectively. This is in accordance with their buried position in the three-dimensional model of the cytosolic Nox2 domain. FAD incorporation is abolished only in the T341K mutant explaining its absence of diaphorase activity. This demonstrates that NADPH oxidase assembly can occur without FAD incorporation. In addition, a defect of NADPH binding is a plausible explanation for the diaphorase activity inhibition in the P415H, P415L, and C537R mutants. In contrast, Cys-369, Gly-408, Leu-546, and Glu-568 are essential for NADPH oxidase complex assembly. However, according to their position in the three-dimensional model of the cytosolic domain of Nox2, only Cys-369 could be in direct contact with cytosolic factors during oxidase assembly. In addition, the defect in oxidase assembly observed in the C369R, G408E, G408R, and E568K mutants correlates with the lack of FAD incorporation. Thus, the NADPH oxidase assembly process and FAD incorporation are closely related events essential for the diaphorase activity of Nox2. 相似文献
7.
Pariyapat Nilsalab Shabbir H. Gheewala Rattanawan Mungkung Sylvain R. Perret Thapat Silalertruksa Sébastien Bonnet 《The International Journal of Life Cycle Assessment》2017,22(11):1666-1677
Purpose
The use and production of biofuels have been strongly promoted in Thailand. In order to achieve a 25 % renewable energy target in 2021, feedstock expansion is needed to satisfy the increased demand for biofuel production putting more pressure on freshwater resources. This is an important implication of biofuel production which has not yet been taken into consideration. Thus, this study intends to address the impact from freshwater use due to the biodiesel target based on life cycle assessment approach as well as to evaluate suitable areas for expansion of oil palm.Methods
The amount of water for growing oil palm throughout its lifespan is estimated based on theoretical crop water requirement, while water demand for producing biodiesel is referred to from literature. Then, the potential impact on freshwater resources is assessed in terms of water deprivation using the water stress index of Thailand. The Alternative Energy Development Plan for 2012–2021 and areas recommended by the Ministry of Agriculture and Cooperatives are referred in this study. Additionally, two scenarios for increasing new plantation in suitable areas are proposed as expansion in a single region or spread over the three regions.Results and discussion
The highest water requirement for oil palm-based biodiesel production is found in the central region followed by the eastern and southern (4–9, 5–16, and 4–19 m3 L?1 biodiesel, respectively). This is because oil palm plantations in the central region are not yet fully mature. As a result, the ratio of crop water requirement associated to crop productivity will be reduced while the water productivity will be increased yearly in yield. Also, more than 99 % of the total water is required during the cultivation period. To achieve the 2021 biodiesel target with a concern towards the impact from freshwater use by means of low water deprivation, cultivating oil palm is recommended entirely in the eastern and the southern parts without expansion to the central region.Conclusions
The impact on freshwater resources is an important implication of biofuel production as most of the water requirement of palm oil biodiesel was for oil palm cultivation. Accounting the water deprivation as one of the criteria on impact from freshwater use will provide useful support for selecting areas having less potential for inducing water stress in a watershed leads to people in these areas being less vulnerable to water stress.8.
Methods based on cutaneous markers are the most popular for the recording of three dimensional scapular motion analysis. Numerous methods have been evaluated, each showing different levels of accuracy and reliability. The aim of this review was to report the metrological properties of 3D scapular kinematic measurements using cutaneous markers and to make recommendations based on metrological evidence. 相似文献
9.
10.