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排序方式: 共有195条查询结果,搜索用时 15 毫秒
1.
Cell-cell recognition 总被引:1,自引:0,他引:1
A Monroy 《Biomedicine / [publiée pour l'A.A.I.C.I.G.]》1980,32(3):103-105
The earlier step of morphogenesis is the segregation of cell lines which are homogeneous cell populations each endowed with its own specific developmental program. In order for the program to unfold in each line cells must be endowed with specific surface properties whereby the cells belonging to the same line can recognize each other as such in addition to recognizing those belonging to other cell lines as different. Experiments supporting this view are described. The hypothesis is presented that the cell-cell recognition system is phylogenetically linked with the invention of sexuality. 相似文献
2.
A jelly precipitating factor was obtained from the eggs of Arbacia punctulata. The eggs were frozen and dried, extracted with 1 M KCl solution and thereafter submitted to ultracentrifugation. A fraction sedimenting following centrifugation for 45 minutes at 25000 × g presented no demonstrable activity. A second fraction, however, obtained following centrifugation for two hours at 155 000 × g gave a highly active fraction, whereas the supernatant proved to be inactive. The active fraction was shown by electrophoresis and ultracentrifugation to contain at least two components. 相似文献
3.
A. Monroy 《Development genes and evolution》1937,137(1):25-33
Zusammenfassung Bei 215 Exemplaren vonTriton taeniatus undalpestris wurde die Linsenregeneration vor und nach der Metamorphose studiert, um deren Wirkung auf die regenerativen Prozesse festzustellen.DieDifferenzierungsgeschwindigkeit der Regenerate steigt bei Tieren vor der Metamorphose bis zu einem Maximum an. Dieses findet man bei voll entwickelten Larven, die aber noch nicht in die Metamorphose eingetreten sind. WÄhrend der Metamorphose sinkt die Differenzierungsgeschwindigkeit der Regenerate betrÄchtlich und steigt nach vollendeter Metamorphose wieder etwas an, ohne jedoch das Maximum des Larvenstadiums zu erreichen.Die absolute Volumenzunahme der Regenerate steht in direktem VerhÄltnis zur Tiergrö\e. Sie ist daher bei den erwachsenen Tieren am grö\ten. WÄhrend der Metamorphose erleidet aber auch sie eine klare Depression.Die spezifische Volumenzunahme des Regenerats, die sich aus dem VerhÄltnis der Grö\e des Regenerats zur Grö\e des Tieres bzw. der normalen Linse in einem bestimmten Stadium ergibt, nimmt mit zunehmender Tiergrö\e, d. h. normalerweise mit dem Alter ab.WÄhrend dieser Forschungen geno\ der Verf. ein Stipendium des «Consiglio Nazionale delle Ricerche». 相似文献
4.
Levans produced by four Zymomonas mobilis strains showed antitumour activity against sarcoma 180 and Ehrlich carcinoma in Swiss albino mice. Levans from two strains (ZAP and CP4) had the highest effects. NMR analysis showed that the polymers were composed only of fructose units. The results suggested that the antineoplasic effect is associated to the polysaccharide molecular weight and that a particular molecular weight range may be responsible for this effect. 相似文献
5.
6.
Roshan Dsouza Darold R. Spillman Ronit Barkalifa Guillermo L. Monroy Eric J. Chaney Karen C. White Stephen A. Boppart 《Journal of biophotonics》2019,12(5)
The formation of biofilms in the endotracheal tubes (ETTs) of intubated patients on mechanical ventilation is associated with a greater risk of ventilator‐associated pneumonia and death. New technologies are needed to detect and monitor ETTs in vivo for the presence of these biofilms. Longitudinal OCT imaging was performed in mechanically ventilated subjects at 24‐hour intervals until extubation to detect the formation and temporal changes of in vivo ETT biofilms. OCT‐derived attenuation coefficient images were used to differentiate between mucus and biofilm. Extubated ETTs were examined with optical and electron microscopy, and all imaging results were correlated with standard‐of‐care clinical test reports. OCT and attenuation coefficient images from four subjects were positive for ETT biofilms and were negative for two subjects. The processed and stained extubated ETTs and clinical reports confirmed the presence/absence of biofilms in all subjects. Our findings confirm that OCT can detect and differentiate between biofilm‐positive and biofilm‐negative groups (P < 10?5). OCT image‐based features may serve as biomarkers for direct in vivo detection of ETT biofilms and help drive investigation of new management strategies to reduce the incidence of VAP. 相似文献
7.
Paulo FP Pimenta Alessandra S Orfano Ana C Bahia Ana PM Duarte Claudia M Ríos-Velásquez Fabrício F Melo Felipe AC Pessoa Giselle A Oliveira Keillen MM Campos Luis Martínez Villegas Nilton Barnabé Rodrigues Rafael Nacif-Pimenta Rejane C Sim?es Wuelton M Monteiro Rogerio Amino Yara M Traub-Cseko José BP Lima Maria GV Barbosa Marcus VG Lacerda Wanderli P Tadei Nágila FC Secundino 《Memórias do Instituto Oswaldo Cruz》2015,110(1):23-47
In the Americas, areas with a high risk of malaria transmission are mainly located in
the Amazon Forest, which extends across nine countries. One keystone step to
understanding the Plasmodium life cycle in Anopheles species from the Amazon Region
is to obtain experimentally infected mosquito vectors. Several attempts to colonise
Ano- pheles species have been conducted, but with only short-lived success or no
success at all. In this review, we review the literature on malaria transmission from
the perspective of its Amazon vectors. Currently, it is possible to develop
experimental Plasmodium vivax infection of the colonised and field-captured vectors
in laboratories located close to Amazonian endemic areas. We are also reviewing
studies related to the immune response to P. vivax infection of Anopheles aquasalis,
a coastal mosquito species. Finally, we discuss the importance of the modulation of
Plasmodium infection by the vector microbiota and also consider the anopheline
genomes. The establishment of experimental mosquito infections with Plasmodium
falciparum, Plasmodium yoelii and Plasmodium berghei parasites that could provide
interesting models for studying malaria in the Amazonian scenario is important.
Understanding the molecular mechanisms involved in the development of the parasites
in New World vectors is crucial in order to better determine the interaction process
and vectorial competence. 相似文献
8.
Paola L. Carvajal Monroy Zipora Yablonka-Reuveni Sander Grefte Anne Marie Kuijpers-Jagtman Frank A.D.T.G. Wagener Johannes W. Von den Hoff 《Journal of visualized experiments : JoVE》2015,(101)
Fibrosis and defective muscle regeneration can hamper the functional recovery of the soft palate muscles after cleft palate repair. This causes persistent problems in speech, swallowing, and sucking. In vitro culture systems that allow the study of satellite cells (myogenic stem cells) from head muscles are crucial to develop new therapies based on tissue engineering to promote muscle regeneration after surgery. These systems will offer new perspectives for the treatment of cleft palate patients. A protocol for the isolation, culture and differentiation of satellite cells from head muscles is presented. The isolation is based on enzymatic digestion and trituration to release the satellite cells. In addition, this protocol comprises an innovative method using extracellular matrix gel coatings of millimeter size, which requires only low numbers of satellite cells for differentiation assays. 相似文献
9.
Andrea P. Castillo‐Monroy Matthew A. Bowker Fernando T. Maestre Susana Rodríguez‐Echeverría Isabel Martinez Claudia E. Barraza‐Zepeda Cristina Escolar 《植被学杂志》2011,22(1):165-174
Questions: To what degree do biological soil crusts (BSCs), which are regulators of the soil surface boundary, influence associated microbial communities? Are these associations important to ecosystem functioning in a Mediterranean semi‐arid environment? Location: Gypsum outcrops near Belmonte del Tajo, Central Spain. Methods: We sampled a total of 45 (50 cm × 50 cm) plots, where we estimated the cover of every lichen and BSC‐forming lichen species. We also collected soil samples to estimate bacterial species richness and abundance, and to assess different surrogates of ecosystem functioning. We used path analysis to evaluate the relationships between the richness/abundance of above‐ and below‐ground species and ecosystem functioning. Results: We found that the greatest direct effect upon the ecosystem function matrix was that of the biological soil crust (BSC) richness matrix. A few bacterial species were sensitive to the lichen community, with a disproportionate effect of Collema crispum and Toninia sedifolia compared to their low abundance and frequency. The lichens Fulgensia subbracteata and Toninia spp. also had negative effects on bacteria, while Diploschistes diacapsis consistently affected sensitive bacteria, sometimes positively. Despite these results, very few of the BSC effects on ecosystem function could be ascribed to changes within the bacterial community. Conclusion: Our results suggest the primary importance of the richness of BSC‐forming lichens as drivers of small‐scale changes in ecosystem functioning. This study provides valuable insights on semi‐arid ecosystems where plant cover is spatially discontinuous and ecosystem function in plant interspaces is regulated largely by BSCs. 相似文献
10.
Fernando A. Monteiro Tatiana Peretolchina Cristiano Lazoski Kecia Harris Ellen M. Dotson Fernando Abad-Franch Elsa Tamayo Pamela M. Pennington Carlota Monroy Celia Cordon-Rosales Paz Maria Salazar-Schettino Andrés Gómez-Palacio Mario J. Grijalva Charles B. Beard Paula L. Marcet 《PloS one》2013,8(8)