全文获取类型
收费全文 | 4307篇 |
免费 | 351篇 |
出版年
2021年 | 54篇 |
2020年 | 44篇 |
2019年 | 40篇 |
2018年 | 68篇 |
2017年 | 56篇 |
2016年 | 110篇 |
2015年 | 157篇 |
2014年 | 176篇 |
2013年 | 261篇 |
2012年 | 327篇 |
2011年 | 345篇 |
2010年 | 207篇 |
2009年 | 203篇 |
2008年 | 285篇 |
2007年 | 276篇 |
2006年 | 275篇 |
2005年 | 243篇 |
2004年 | 234篇 |
2003年 | 243篇 |
2002年 | 244篇 |
2001年 | 41篇 |
2000年 | 34篇 |
1999年 | 43篇 |
1998年 | 60篇 |
1997年 | 35篇 |
1996年 | 33篇 |
1995年 | 37篇 |
1994年 | 35篇 |
1993年 | 28篇 |
1992年 | 25篇 |
1991年 | 20篇 |
1990年 | 28篇 |
1989年 | 18篇 |
1988年 | 14篇 |
1987年 | 16篇 |
1985年 | 18篇 |
1984年 | 18篇 |
1983年 | 17篇 |
1982年 | 17篇 |
1981年 | 17篇 |
1980年 | 11篇 |
1979年 | 16篇 |
1978年 | 13篇 |
1977年 | 13篇 |
1976年 | 17篇 |
1975年 | 12篇 |
1974年 | 16篇 |
1972年 | 13篇 |
1969年 | 9篇 |
1963年 | 8篇 |
排序方式: 共有4658条查询结果,搜索用时 31 毫秒
1.
Response of Picea rubens seedlings to intermittent mist varying in acidity, and in concentrations of sulfur-, and nitrogen-containing pollutants 总被引:7,自引:0,他引:7
Jay S. Jacobson Twylene Bethard Laurence I. Heller James P. Lassoie 《Physiologia plantarum》1990,78(4):595-601
Two-year-old red spruce seedlings ( Picea rubens Sarg .) growing in. field chambers were repeatedly exposed to acidic mist with a factorial combination of 3 fluctuating levels of acidity: median pH values of 3.0 (range of 2.5 to 3.5), 3.5 (range of 3.0 to 4.0), and 4.0 (range of 3.5 to 4.5). and 3 ion compositions: sulfate. nitrate and ammonium, and a combination of all 3 ions. The experiment was performed during the growing season over a period of 3.5 months. Mist exposures were intermittent with 5 wet-dry cycles for each 16-h overnight exposure period, Foliar necrosis occurred on seedlings treated with the most acidic mist and was most severe when the mist contained sulfate. At a median pH of 3.5, a value close to that of cloud water occurring in the eastern United States, injury developed with sulfuric acid mist, but not. when the mist contained nitric acid. The combination of high acidity and sulfate significantly decreased volume of aboveground tissues, while high acidity and nitrate increased volume. Root and needle dry weights were not affected. However, high acidity of mist was associated with increased leader shoot length. These results indicate, that there is a risk of foliar injury and changes in growth of red spruce with cloud water at a median acidity of pH 3.5 or below, especially when there are high concentrations of sulfate and low concentrations of nitrate. 相似文献
2.
The resorption of unemitted gametes during the post-spawning period of the male and female reproductive cycles in Lithognathus mormyrus was studied by histochemical, histological and cytological methods. The resorption of residual spermatozoa involved the phagocytotic activity of Sertoli cells bounding the seminiferous cysts of spermatozoa, and those associated with spermatogonia lining the lobular lumen. Spermatozoa remaining in the sperm duct were phagocytozed by the lining epithelial cells. Eosinophilic granulocytes and macrophages were identified in the vicinity of residual spermatozoa. The remnants of oocytes underwent an atretic phenomenon in which follicle cells were firstly involved, inducing a progressive fragmentation of the oocyte cytoplasm. Subsequently, eosinophilic granulocytes invaded oocyte degenerative areas and clung to the remaining vitelline inclusions ensuring their biotransformation into waste products (brown bodies). The analogy of the resorption processes of both male and female unemitted gametes during the post-spawning period of natural reproductive cycle, involving first the enveloping somatic cells and then immune cells, is emphasized. 相似文献
3.
Gérard Sarazin Jean-Fran cois Gaillard Laurence Philippe Christophe Rabouille 《Hydrobiologia》1995,315(2):95-118
The chemical composition of the pore water from the sediment of a eutrophic lake is dominated by high concentrations of total dissolved CO2 (up to 12 mM), reduced soluble iron (up to 2 mM) and dissolved silica (up to 1 mM). The pH lies within the range of 6.70 ± 0.02; this reflects that the pore water is efficiently buffered by the CO2 acid/base system. This composition is directly related to the main diagenetic reactions which drive the organic matter mineralization i.e. methanogenesis and ferric oxides reduction. Other geochemical processes are of minor importance. A stoichiometric model based on these main reactions allow us: (i) to define a general formula for the organic matter which is close to Redfield's one for the C:N ratio, while the C:P ratio is much higher owing to a probable adsorption of phosphorus onto reactive surfaces of the solid and due to heterotrophic bacterial uptake; (ii) to calculate a global first order kinetic constant which drives the organo-polymers breakdown. Due to the strong influence on the trophic status of the lake caused by an excess of phosphate, special attention is devoted to this species. We show that the sediment-water interface is a source of dissolved phosphate when the hypolimnion is anoxic between May and November. This contribution represents about 17% of the river input and should be taken into account in any attempt toward lake restoration. 相似文献
4.
Gilberto Sousa Alves Laurence O’Dwyer Alina Jurcoane Viola Oertel-Kn?chel Christian Kn?chel David Prvulovic Felipe Sudo Carlos Eduardo Alves Letice Valente Denise Moreira Fabian Fuβer Tarik Karakaya Johannes Pantel Eliasz Engelhardt Jerson Laks 《PloS one》2012,7(12)
Alzheimeŕs disease (AD) represents the most prevalent neurodegenerative disorder that causes cognitive decline in old age. In its early stages, AD is associated with microstructural abnormalities in white matter (WM). In the current study, multiple indices of diffusion tensor imaging (DTI) and brain volumetric measurements were employed to comprehensively investigate the landscape of AD pathology. The sample comprised 58 individuals including cognitively normal subjects (controls), amnestic mild cognitive impairment (MCI) and AD patients. Relative to controls, both MCI and AD subjects showed widespread changes of anisotropic fraction (FA) in the corpus callosum, cingulate and uncinate fasciculus. Mean diffusivity and radial changes were also observed in AD patients in comparison with controls. After controlling for the gray matter atrophy the number of regions of significantly lower FA in AD patients relative to controls was decreased; nonetheless, unique areas of microstructural damage remained, e.g., the corpus callosum and uncinate fasciculus. Despite sample size limitations, the current results suggest that a combination of secondary and primary degeneration occurrs in MCI and AD, although the secondary degeneration appears to have a more critical role during the stages of disease involving dementia. 相似文献
5.
Eric L. Stevens Joseph D. Baugher Matthew D. Shirley Laurence P. Frelin Jonathan Pevsner 《PloS one》2012,7(11)
Correct annotation of the genetic relationships between samples is essential for population genomic studies, which could be biased by errors or omissions. To this end, we used identity-by-state (IBS) and identity-by-descent (IBD) methods to assess genetic relatedness of individuals within HapMap phase III data. We analyzed data from 1,397 individuals across 11 ethnic populations. Our results support previous studies (Pemberton et al., 2010; Kyriazopoulou-Panagiotopoulou et al., 2011) assessing unknown relatedness present within this population. Additionally, we present evidence for 1,657 novel pairwise relationships across 9 populations. Surprisingly, significant Cotterman''s coefficients of relatedness K1 (IBD1) values were detected between pairs of known parents. Furthermore, significant K2 (IBD2) values were detected in 32 previously annotated parent-child relationships. Consistent with a hypothesis of inbreeding, regions of homozygosity (ROH) were identified in the offspring of related parents, of which a subset overlapped those reported in previous studies (Gibson et al. 2010; Johnson et al. 2011). In total, we inferred 28 inbred individuals with ROH that overlapped areas of relatedness between the parents and/or IBD2 sharing at a different genomic locus between a child and a parent. Finally, 8 previously annotated parent-child relationships had unexpected K0 (IBD0) values (resulting from a chromosomal abnormality or genotype error), and 10 previously annotated second-degree relationships along with 38 other novel pairwise relationships had unexpected IBD2 (indicating two separate paths of recent ancestry). These newly described types of relatedness may impact the outcome of previous studies and should inform the design of future studies relying on the HapMap Phase III resource. 相似文献
6.
7.
Kennedy Linda M.; Saul Laurence R.; Sefecka Richard; Stevens David A. 《Chemical senses》1988,13(4):529-543
An aqueous extract of Hovenia dulcis leaves selectively reducedsweetness perception in humans. The taste-active principle,hodulcin, was partially purified and comparedchromatographically with similarly prepared samples of the selective,sweetness-reducing compounds, gymnemic acids and ziziphins.Hodulcin appears to be a triterpene saponin glycoside, as arethe gymnemic acids and ziziphins. Nuclear magnetic resonance(NMR) spectra indicated an hodulcin aglycone structure differentfrom the gymnemic acids aglycone, and similar to, but not thesame as the ziziphins aglycone. Future comparative studies ofthe actions of hodulcin, gymnemic acids and ziziphins couldelucidate physiological mechanisms for the transduction andidentification of sweet stimuli and aid the development of newapproaches to the sweetening of foods. 相似文献
8.
9.
10.