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Halil Erhan Eroğlu Ahmet Aksoy Ergin Hamzaoğlu Ümit Budak Sevil Albayrak 《Cytotechnology》2009,59(1):65-72
Helichrysum Mill. (Asteraceae) species have been used in folk medicine for thousands of years in the world. The in vitro cytogenetic
effects in human lymphocytes of nine Helichrysum taxa used in Turkey folk medicine were investigated. Blood samples were obtained from healthy donors, non-smoking volunteers,
which were incubated and exposed to increasing concentrations of methanol extracts of Helichrysum taxa (0.01, 0.05, 0.1, 0.5 and 1 mg/mL). The inhibitory effects of H. stoechas (L.) Moench subsp. barrelieri (Ten.) Nyman, H. armenium DC. subsp. armenium, H. armenium DC. subsp. araxinum (Kirp.) Takht., H. plicatum DC. subsp. plicatum, H. compactum Boiss. and H. artvinense P.H.Davis & Kupicha on the mitotic index and replication index indicate that these taxa can have genotoxic and mutagenic
effects. They should therefore not be used freely in alternative medicine although their antiproliferative activity may suggest
anticarcinogenic properties. Increase effects of H. stoechas subsp. barrelieri, H. armenium subsp. armenium, H. armenium subsp. araxinum, H. chasmolycicum P.H.Davis, H. plicatum subsp. plicatum, H. compactum and H. artvinense on the micronucleus rates showed that these taxa can have genotoxic and carcinogenic effects. 相似文献
3.
Heteroduplex formation is known to occur during mixed-template polymerase chain reaction (PCR) using universal primers, and
may represent a serious problem in several PCR-based analyses. A common way to eliminate heteroduplex formation is to use
reconditioning PCR. Because we detected that reconditioning PCR was not always sufficient to prevent heteroduplex formation,
we focused on developing methods for the elimination of heteroduplexes during PCR. We detected that the heteroduplex to homoduplex
ratio can be decreased by the addition of Taq polymerase and by a decrease in the number of PCR cycles. An appropriate combination of both of these approaches can be a
method generally applicable to decrease the formation of heteroduplexes. 相似文献
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C D Olinici E R?dulescu I C?lu?er M Giurgiuman I Macavei E Marinca 《Morphologie et embryologie》1980,26(4):341-344
The incidence of micronuclei in bone marrow erythroblasts of patients with pernicious anemia ranged between 0.5-5.6% as compared with the value of 0-0.5% noted in hematologically healthy patients. The mechanism of formation and the possible significance of micronuclei in megaloblastic anemia are briefly discussed. 相似文献
6.
The frequency of the palatine torus varies in various populations from different regions of the world. In this study, the change of frequency of palatine torus is examined using 387 skulls from 12 different ancient Anatolian populations in various periods ranging from the Early Bronze Age to the first quarter of the 20th century.While the frequency of palatine torus is 45% in the Early Bronze Age, this ratio steadily increases to 87% in the Ottoman Period and finally declines to 40% during the recent period. It was determined that the increase in the frequency of the palatine torus is statistically significant across different periods from the Early Bronze Age until the 20th century. Constituting a passageway between Asia and Europe and being located on the crossroads of the most important trade route of the Medieval Period, the Silk Road, Anatolia is known to have been subjected to recurring invasions and migrations since the 11th century A.D. Therefore, it is possible to say that, with the introduction of the Mongoloid influence in Anatolia, genetic flow has had a significant role in the observed increase in the frequency of this trait. 相似文献
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Mustafa Çulha Şaban Kalay Elif Sevim Müberra Pinarbaş Yıldız Baş Rahşan Akpinar Şengül Alpay Karaoğlu 《Biometals》2017,30(6):893-902
Bee disease caused by spore-forming Paenibacillus larvae and Paenibacillus alvei is a serious problem for honey production. Thus, there is an ongoing effort to find an effective agent that shows broad biocidal activity with minimal environmental hazard. In this study, the biocidal effect of maltose reduced silver nanoparticles (AgNPs) is evaluated against American foulbrood and European foulbrood pathogens. The results demonstrate that the maltose reduced AgNPs are excellent short and long-term biocides against P. larvae isolates. The long-term effect suggests that the Ag+ ions are released from the AgNPs with increasing time in a controlled manner. 相似文献
9.
Zaimoğlu Elif Hoxha Saimir Özdiler Orhan Özbek Murat Memikoğlu Ufuk Toygar 《Sleep and biological rhythms》2017,15(1):75-80
Sleep and Biological Rhythms - This study aimed to identify the symptoms and prevalence of snoring among primary school children in Ankara, Turkey, as reported by their parents and to determine the... 相似文献
10.
Journal of Plant Growth Regulation - Herbicides inhibit plant growth and development by various mechanisms, and oxidative stress is a common plant response to herbicide treatment. In a limited... 相似文献