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Selective method for identification and quantification of Bifidobacterium animalis subspecies lactis BB‐12 (BB‐12) from the gastrointestinal tract of healthy volunteers ingesting a combination probiotic of BB‐12 and Lactobacillus rhamnosus GG 下载免费PDF全文
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Detection and genotyping of group A rotaviruses isolated from sewage samples in Monastir,Tunisia between April 2007 and April 2010 下载免费PDF全文
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Daniela Bellicoso Maureen Trudeau Margaret I. Fitch Martin R. Ralph 《Chronobiology international》2017,34(6):808-818
Primary caregivers for victims of chronic illness and or trauma experience both positive and negative emotional consequences. These are broadly classified as compassion satisfaction (CS) and compassion fatigue (CF). Because one of the components of CF, burnout, varies with chronotype and sleep quality, we assessed the influence of chronobiological features on the broader constructs of CS and CF. Responses from primary ambulatory care oncology staff working dayshifts were assessed for potential relationships of chronotype and sleep quality with CS and CF using the professional quality of life scale. These were analyzed further in a multivariate model that included personality and job satisfaction as cofactors. We found that sleep quality was a key contributor to CS development and CF reduction. Morningness was positively linked to CS, but the univariate association was masked in the multivariate model. Job satisfaction (contingent rewards, nature of work and operating procedures) heavily influenced CS and CF development. Agreeableness and openness showed positive correlations with CS and negative with burnout, while emotional stability was linked to reduced CF. While job satisfaction and personality predictably played roles in the development of CS and CF, sleep quality and chronotype contributed significantly to benefits and negative consequences of providing care. 相似文献
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E.?V.?EismontEmail author S.?A.?Makhin A.?V.?Bakunova A.?I.?Kaida V.?B.?Pavlenko 《Human physiology》2017,43(3):274-279
We studied the frequency and amplitude properties of the EEG μ rhythm in children (n = 38) aged 4–14 years under the condition of visual fixation (VF) on a video image of a computer mouse, as well as the parameters of its desynchronization during the tasks involving self-controlled performance, observation, imitation, and auditory recognition of the hand circular movements (SPM, OM, IM, and ARM, respectively) with a computer mouse. We observed age-related increment in the modal frequency of μ rhythm in loci C 3 and C z. During the SPM process, a significant decrease in the amplitude of μ rhythm was found in loci C 3 (26.7%) and C z (10.3%); during the OM, in locus C z only (9.9%). The effects of the μ rhythm desynchronization during both self-paced and observed movements might be an evidence of well-developed neural matching mechanisms that provide the processes of performing and observing similar actions in children aged 4 to 14 years. During the IM, the desynchronization of μ rhythm was significant in loci C 3 (27.4%) and C z (15.3%). We hypothesize that the statistically significant increase (from SPM to IM) in the depression of μ rhythm in locus C z is likely to be an effect of a social gaming context common for the situations when children imitate the movements of adults. The index of desynchronization of μ rhythm under the studied conditions did not depend on the age of children. Possible relations of identified modulations of the μ rhythm to the activity of the mirror neuron system were also discussed. 相似文献
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Fabiana K. Ludka Tharine Dal-Cim Luisa Bandeira Binder Leandra Celso Constantino Caio Massari Carla I. Tasca 《Molecular neurobiology》2017,54(5):3149-3161
Atorvastatin has been shown to exert a neuroprotective action by counteracting glutamatergic toxicity. Recently, we have shown atorvastatin also exerts an antidepressant-like effect that depends on both glutamatergic and serotonergic systems modulation. Excitotoxicity is involved in several brain disorders including depression; thus, it is suggested that antidepressants may target glutamatergic system as a final common pathway. In this study, a comparison of the mechanisms involved in the putative neuroprotective effect of a repetitive atorvastatin or fluoxetine treatment against glutamate toxicity in hippocampal slices was performed. Adult Swiss mice were treated with atorvastatin (10 mg/kg, p.o.) or fluoxetine (10 mg/kg, p.o.), once a day during seven consecutive days. On the eighth day, animals were killed and hippocampal slices were obtained and subjected to an in vitro protocol of glutamate toxicity. An acute treatment of atorvastatin or fluoxetine was not neuroprotective; however, the repeated atorvastatin or fluoxetine treatment prevented the decrease in cellular viability induced by glutamate in hippocampal slices. The loss of cellular viability induced by glutamate was accompanied by increased D-aspartate release, increased reactive oxygen species (ROS) and nitric oxide (NO) production, and impaired mitochondrial membrane potential. Atorvastatin or fluoxetine repeated treatment also presented an antidepressant-like effect in the tail suspension test. Atorvastatin or fluoxetine treatment was effective in protecting mice hippocampal slices from glutamate toxicity by preventing the oxidative stress and mitochondrial dysfunction. 相似文献
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Effects of experimental warming on survival,phenology, and morphology of an aquatic insect (Odonata) 下载免费PDF全文
SHANNON J. MCCAULEY JOHN I. HAMMOND DACHIN N. FRANCES KAREN E. MABRY 《Ecological Entomology》2015,40(3):211-220
1. Organisms can respond to changing climatic conditions in multiple ways including changes in phenology, body size or morphology, and range shifts. Understanding how developmental temperatures affect insect life‐history timing and morphology is crucial because body size and morphology affect multiple aspects of life history, including dispersal ability, whereas phenology can shape population performance and community interactions. 2. It was experimentally assessed how developmental temperatures experienced by aquatic larvae affected survival, phenology, and adult morphology of dragonflies [Pachydiplax longipennis (Burmeister)]. Larvae were reared under three environmental temperatures: ambient, +2.5, and +5 °C, corresponding to temperature projections for our study area 50 and 100 years in the future, respectively. Experimental temperature treatments tracked naturally‐occurring variation. 3. Clear effects of temperature were found in the rearing environment on survival and phenology: dragonflies reared at the highest temperatures had the lowest survival rates and emerged from the larval stage approximately 3 weeks earlier than animals reared at ambient temperatures. There was no effect of rearing temperature on overall body size. Although neither the relative wing nor thorax size was affected by warming, a non‐significant trend towards an interaction between sex and warming in relative thorax size suggests that males may be more sensitive to warming than females, a pattern that should be investigated further. 4. Warming strongly affected survival in the larval stage and the phenology of adult emergence. Understanding how warming in the developmental environment affects later life‐history stages is critical to interpreting the consequences of warming for organismal performance. 相似文献
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