全文获取类型
收费全文 | 50209篇 |
免费 | 4267篇 |
国内免费 | 2972篇 |
出版年
2023年 | 580篇 |
2022年 | 660篇 |
2021年 | 2090篇 |
2020年 | 1618篇 |
2019年 | 2016篇 |
2018年 | 1871篇 |
2017年 | 1348篇 |
2016年 | 2057篇 |
2015年 | 2990篇 |
2014年 | 3640篇 |
2013年 | 3852篇 |
2012年 | 4665篇 |
2011年 | 4193篇 |
2010年 | 2599篇 |
2009年 | 2198篇 |
2008年 | 2523篇 |
2007年 | 2273篇 |
2006年 | 1960篇 |
2005年 | 1689篇 |
2004年 | 1478篇 |
2003年 | 1274篇 |
2002年 | 1115篇 |
2001年 | 951篇 |
2000年 | 953篇 |
1999年 | 924篇 |
1998年 | 558篇 |
1997年 | 491篇 |
1996年 | 508篇 |
1995年 | 455篇 |
1994年 | 428篇 |
1993年 | 297篇 |
1992年 | 460篇 |
1991年 | 360篇 |
1990年 | 383篇 |
1989年 | 308篇 |
1988年 | 222篇 |
1987年 | 186篇 |
1986年 | 161篇 |
1985年 | 159篇 |
1984年 | 111篇 |
1983年 | 102篇 |
1982年 | 67篇 |
1981年 | 53篇 |
1979年 | 71篇 |
1978年 | 54篇 |
1977年 | 53篇 |
1975年 | 59篇 |
1974年 | 48篇 |
1973年 | 50篇 |
1972年 | 41篇 |
排序方式: 共有10000条查询结果,搜索用时 15 毫秒
1.
Circulating long non‐coding RNAs NRON and MHRT as novel predictive biomarkers of heart failure 下载免费PDF全文
2.
An advanced electro-active dry adhesive,which was composed of a mushroom-shaped fibrillar dry adhesive array actuated by an Ionic Polymer Metal Composite (IPMC) artificial muscle reinforced with nitrogen-doped carbon nanocages (NCNCs),was developed to imitate the actuation of a gecko's toe.The properties of the NCNC-reinforced Nafion membrane,the electromechanical properties of the NCNC-reinforced IPMC,and the related electro-active adhesion ability were investigated.The NCNCs were uniformly dispersed in the 0.1 wt% NCNC/Nafion membrane,and there was a seamless connection with no clear interface between the dry adhesive and the IPMC.Our 0.1 wt% NCNC/Nafion-IPMC actuator shows a displacement and force that are 1.6-2 times higher than those of the recast Nafion-IPMC.This is due to the increased water uptake (25.39%) and tensile strength (24.5 MPa) of the specific 3D hollow NCNC-reinforced Nafion membrane,as well as interactions between the NCNCs and the sulfonated groups of the Nafion.The NCNC/Nafion-IPMC was used to effectively actuate the mushroom-shaped dry adhesive.The normal adhesion forces were 7.85 mN,12.1 mN,and 51.7 mN at sinusoidal voltages of 1.5 V,2.5 V,and 3.5 V,respectively,at 0.1 Hz.Under the bionic leg trail,the normal and shear forces were approximately 713.5 mN (159 mN·cm-2) and 1256.6 mN (279 mN·cm-2),respectively,which satisfy the required adhesion.This new electro-active dry adhesive can be applied for active,distributed actuation and flexible grip in robots. 相似文献
3.
Zhengqi Liu Guolan Fu Zhenping Huang Jing Chen Xiaoshan Liu 《Plasmonics (Norwell, Mass.)》2017,12(3):577-582
All-dielectric resonant structure (ADRS) consisting of high-index nonlinear dielectrics has been theoretically and numerically demonstrated with multi-band ultra-sharp transmission response in this work. Bandwidth down to sub-nanometer and spectral Q-factor up to 920 are achieved in this ADRS-based metamaterial-like platform. Strong resonant electric field distributions by the high-index dielectric resonators and efficient coupling between the layered dielectric particles and the cavity mainly contribute to the multiple narrowband light transmission filtering. By using a Kerr nonlinear medium as the resonant dielectric, the positions of the transmission dips in the spectrum can be actively tuned by the incident light intensity. Due to the ultra-narrow spectral feature and the strong electric field distribution by the resonators, an efficient all-optical switching behavior with high spectral difference intensity and contrast ratio is obtained. Further study presents the observed multi-band transmission with high scalability by tuning the structural parameters. These optical features hold the predicted ADRS be potentially applied to constructing dielectric metamaterial-based all-optical switching or active subtractive transmission filtering with low power threshold at sub-diffraction scale. 相似文献
4.
5.
6.
Biochar adsorption presents a potential remediation method for the control of hydrophobic organic compounds (HOCs) pollution in the environment. It has been found that HOCs bound on biochar become less bioavailable, so speculations have been proposed that HOCs will persist for longer half-life periods in biochar-amended soil/sediment. To investigate how biochar application affects coupled adsorption-biodegradation, nonylphenol was selected as the target contaminant, and biochar derived from rice straw was applied as the adsorbent. The results showed that there was an optimal dosage of biochar in the presence of both adsorption and biodegradation for a given nonylphenol concentration, thus allowing the transformation of nonylphenol to be optimized. Approximately 47.6% of the nonylphenol was biodegraded in two days when 0.005 g biochar was added to 50 mg/L of nonylphenol, which was 125% higher than the relative quantity biodegraded without biochar, though the resistant desorption component of nonylphenol reached 87.1%. All adsorptive forms of nonylphenol (f
rap, f
slow, f
r) decreased gradually during the biodegradation experiment, and the resistant desorption fraction of nonylphenol (f
r) on biochar could also be biodegraded. It was concluded that an appropriate amount of biochar could stimulate biodegradation, not only illustrating that the dosage of biochar had an enormous influence on the half-life periods of HOCs but also alleviating concerns that enhanced HOCs binding by biochar may cause secondary pollution in biochar-modified environment. 相似文献
7.
8.
9.
Currently, many diabetic cardiomyopathy (DC) studies focus on either in vitro molecular pathways or in vivo whole-heart properties such as ejection fraction. However, as DC is primarily a disease caused by changes in structural and functional properties, such studies may not precisely identify the influence of hyperglycemia or hyperlipidemia in producing specific cellular changes, such as increased myocardial stiffness or diastolic dysfunction. To address this need, we developed an in vitro approach to examine how structural and functional properties may change as a result of a diabetic environment. Particle-tracking microrheology was used to characterize the biomechanical properties of cardiac myocytes and fibroblasts under hyperglycemia or hyperlipidemic conditions. We showed that myocytes, but not fibroblasts, exhibited increased stiffness under diabetic conditions. Hyperlipidemia, but not hyperglycemia, led to increased cFos expression. Although direct application of reactive oxygen species had only limited effects that altered myocyte properties, the antioxidant N-acetylcysteine had broader effects in limiting glucose or fatty-acid alterations. Changes consistent with clinical DC alterations occur in cells cultured in elevated glucose or fatty acids. However, the individual roles of glucose, reactive oxygen species, and fatty acids are varied, suggesting multiple pathway involvement. 相似文献
10.
Hongtao Zhang Xiaojing Wang Michael J. Giroux Li Huang 《Molecular Plant Pathology》2017,18(1):125-133
The COP9 (constitutive photomorphogenesis 9) signalosome (CSN) is a protein complex involved in the ubiquitin proteasome system and a common host target of diverse pathogens in Arabidopsis. The known derubylation function of the COP9 complex is carried out by subunit 5 encoded by AtCSN5A or AtCSN5B in Arabidopsis. A single CSN5‐like gene (designated as TaCSN5) with three homeologues was identified on the long arms of wheat (Triticum aestivum L.) group 2 chromosomes. In this study, we identified and characterized the function of TaCSN5 in response to infection by the leaf rust pathogen. Down‐regulation of all three TaCSN5 homeologues or mutations in the homeologues on chromosomes 2A or 2D resulted in significantly enhanced resistance to leaf rust. Enhanced leaf rust resistance corresponded to a seven‐fold increase in PR1 (pathogenesis‐related gene 1) expression. Collectively, the data indicate that the wheat COP9 subunit 5‐like gene acts as a negative regulator of wheat leaf rust resistance. 相似文献