全文获取类型
收费全文 | 895篇 |
免费 | 74篇 |
出版年
2023年 | 5篇 |
2022年 | 3篇 |
2021年 | 27篇 |
2020年 | 19篇 |
2019年 | 21篇 |
2018年 | 12篇 |
2017年 | 19篇 |
2016年 | 28篇 |
2015年 | 50篇 |
2014年 | 49篇 |
2013年 | 63篇 |
2012年 | 66篇 |
2011年 | 58篇 |
2010年 | 28篇 |
2009年 | 32篇 |
2008年 | 42篇 |
2007年 | 36篇 |
2006年 | 43篇 |
2005年 | 50篇 |
2004年 | 38篇 |
2003年 | 36篇 |
2002年 | 34篇 |
2001年 | 10篇 |
2000年 | 8篇 |
1999年 | 15篇 |
1998年 | 3篇 |
1996年 | 6篇 |
1995年 | 5篇 |
1994年 | 9篇 |
1993年 | 6篇 |
1991年 | 4篇 |
1990年 | 8篇 |
1989年 | 5篇 |
1987年 | 8篇 |
1986年 | 5篇 |
1985年 | 3篇 |
1984年 | 4篇 |
1983年 | 8篇 |
1982年 | 6篇 |
1981年 | 7篇 |
1980年 | 7篇 |
1979年 | 4篇 |
1978年 | 7篇 |
1977年 | 6篇 |
1976年 | 7篇 |
1975年 | 13篇 |
1974年 | 11篇 |
1973年 | 11篇 |
1972年 | 4篇 |
1966年 | 3篇 |
排序方式: 共有969条查询结果,搜索用时 15 毫秒
1.
Justin C. Luong Patrick L. Turner Celina N. Phillipson Katja C. Seltmann 《Ecological Entomology》2019,44(4):471-479
1. It is hypothesised that ecological restoration in grasslands can induce an alternative stable state shift in vegetation. The change in vegetation influences insect community assemblages and allows for greater functional redundancy in pollination and refuge for native insect species. 2. Insect community assemblages at eight coastal California grassland sites were evaluated. Half of these sites had undergone restoration through active revegetation of native grassland flora and half were non‐restored. Insects were collected from Lupinus bicolor (Fabaceae) within 2 × 2‐m2 plots in spring 2017. Lupinus bicolor is a common native species that is used in California restoration projects, and home and state landscaping projects. 3. Ordination demonstrated that insect community assemblages were different between restored and non‐restored sites. These differences were seen in insect functional groups as well as taxa‐specific differences and were found to be driven by environmental characteristics such as non‐native forb cover. 4. Functional redundancy of herbivores decreased at restored sites, while pollinators became more redundant compared with non‐restored sites. The assemblages of the common species found at restoration sites contained more native insects than those found at non‐restored sites, including species such as Bombus vosnesenskii. 5. Local grassland restoration has the potential to induce an alternative stable state change and affect insect community assemblages. Additionally, it was found that grassland restoration can be a potential conservation tool to provide refugia for bumblebees (Bombus), but additional studies are required to fully understand its broader applicability. 相似文献
2.
3.
Chung-Te Chang Natalia Bercovich Belinda Loh Stefanie Jonas Elisa Izaurralde 《Nucleic acids research》2014,42(8):5217-5233
The removal of the 5′-cap structure by the decapping enzyme DCP2 and its coactivator DCP1 shuts down translation and exposes the mRNA to 5′-to-3′ exonucleolytic degradation by XRN1. Although yeast DCP1 and DCP2 directly interact, an additional factor, EDC4, promotes DCP1–DCP2 association in metazoan. Here, we elucidate how the human proteins interact to assemble an active decapping complex and how decapped mRNAs are handed over to XRN1. We show that EDC4 serves as a scaffold for complex assembly, providing binding sites for DCP1, DCP2 and XRN1. DCP2 and XRN1 bind simultaneously to the EDC4 C-terminal domain through short linear motifs (SLiMs). Additionally, DCP1 and DCP2 form direct but weak interactions that are facilitated by EDC4. Mutational and functional studies indicate that the docking of DCP1 and DCP2 on the EDC4 scaffold is a critical step for mRNA decapping in vivo. They also revealed a crucial role for a conserved asparagine–arginine containing loop (the NR-loop) in the DCP1 EVH1 domain in DCP2 activation. Our data indicate that DCP2 activation by DCP1 occurs preferentially on the EDC4 scaffold, which may serve to couple DCP2 activation by DCP1 with 5′-to-3′ mRNA degradation by XRN1 in human cells. 相似文献
4.
5.
Belinda Martineau H. Jane Smith Caroline Dean Pamela Dunsmuir John Bedbrook Laurens J. Mets 《Plant molecular biology》1989,13(4):419-426
We report the successful transformation, via Agrobacterium tumefaciens infection, and regeneration of two species of the genus Flaveria: F. brownii and F. palmeri. We document the expression of a C3 plant gene, an abundantly expressed ribulose 1,5-bisphosphate carboxylase/oxygenase small subunit gene isolated from petunia, in these C4 plants. The organ-specific expression of this petunia gene in Flaveria brownii is qualitatively identical to its endogenous pattern of expression. 相似文献
6.
McClean P. A.; Phillipson E. A.; Martinez D.; Zamel N. 《Journal of applied physiology》1988,64(1):84-89
Peripheral chemoreceptor responsiveness is usually examined clinically by hypoxic testing, but the usefulness of this approach is limited by safety considerations, and the interpretation of results may be confounded by the direct central nervous system effects of hypoxia. Therefore we examined the single-breath (SB) CO2 test to determine its reproducibility and applicability as a clinical test of peripheral chemoreceptor function. The technique involved the inhalation of a SB of 13% CO2 in air. The ventilatory response was determined from the increase in ventilation (VE) during the first 20 s after the test breath and from the difference in end-tidal PCO2 between the test breath and preceding control breaths. The peak increase in VE occurred during the second or third breath after the test breath, corresponding to a delay of approximately 10 s. The mean of 10 SB tests administered at 2- to 3-min intervals was taken as the subject's response. Five healthy subjects were tested in this manner on each of 6 consecutive days with the response having an interday coefficient of variation of 25 +/- 6% (SD). The response in 26 healthy females (aged 22-61 yr) was 0.32 +/- 0.11 l.min-1.Torr-1, and in 26 healthy males (aged 24-69 yr) the response was 0.38 +/- 0.14 (P NS). No significant correlation was found between the age of the subjects and their ventilatory response. Thirty-six of the subjects also underwent hyperoxic CO2 rebreathing tests, the response to which is dependent on central chemoreceptor function. No correlation was found between rebreathing and SB tests.(ABSTRACT TRUNCATED AT 250 WORDS) 相似文献
7.
Phillipson JD 《Parasitology today (Personal ed.)》1986,2(12):327-328
8.
N. K. Tawfiq L. A. Anderson M. F. Roberts J. D. Phillipson D. H. Bray D. C. Warhurst 《Plant cell reports》1989,8(7):425-428
Extracts of Artemisia annua cultures have been assessed for in vitro activity against the malarial parasite Plasmodium falciparum. Callus and suspension cells and medium were analysed and examined for their activity at different stages of growth and development. Time-course experiments were carried out to investigate the influence of various basal media, plant growth regulators and light on both growth and possible artemisinin production. Two active fractions were obtained but artemisinin was not detected. 相似文献
9.
10.
A one-dimensional mapping of the binding properties of a linear lattice offers an exact analytical solution for the site-specific properties of the lattice once the length N and the parameter for nearest neighbor interactions are specified. The solution is derived independent of the definition of the partition function or the transfer matrix, nor does it involve combinatorial arguments. This result provides a simple and effective way of analyzing experimental data for protein-ligand interactions and broadens our understanding of site-specific properties in biological macromolecules. 相似文献