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Adriano Garcia Chiarello 《American journal of primatology》1995,36(3):213-222
The loud calls of brown howler monkeys were studied during a year at the Santa Genebra Reserve, in southeastern Brazil. The study group emitted roars and barks on a total of 47 occasions, the majority of which (92%) were restricted to intergroup visual encounters. Loud calls were also elicited by the roars of distant groups (6%) and during intragroup agonistic interactions (2%). Intergroup visual encounters (n = 42) occurred predominantly in seldom used quadrats of the study group home range. In these instances, the loud calls were produced chiefly by the adult male alone (69% of cases), while the study group's two adult females joined the male in the remaining cases. Intergroup physical aggression, such as chase and displacement, was observed during 15 encounters (35% of cases). A dawn chorus does not occur in Santa Genebra—the loud calls were heard most frequently in mid-morning and again during mid-afternoon—and they were more abundant during the dry season, when the availability of food (new leaves) in the forest was lower. The data presented here provide some support for the hypothesis that roars of howler adult males are used in assessment of opponents, providing an alternative to energetically expensive chases and fights. However, given the relatively high rate of physical aggression observed during intergroup encounters, a result probably related to the high density of howlers and the consequent high frequency of intergroup encounters observed in this forest (0.7/day), ritualized aggression, in the form of loud calling, is apparently often insufficient to settle disputes. © 1995 Wiley-Liss, Inc. 相似文献
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Rasheed Faisal Anjum Naser A. Masood Asim Sofo Adriano Khan Nafees A. 《Journal of Plant Growth Regulation》2022,41(5):1891-1904
Journal of Plant Growth Regulation - The salinization of agriculture soils over the globe has become one of the most devastating stresses and is significantly limiting cultivated land area, and... 相似文献
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Gustavo Souto de Sá e Souza Fábio Barbosa Rodrigues Adriano O. Andrade Marcus Fraga Vieira 《Computer methods in biomechanics and biomedical engineering》2017,20(8):901-904
Gait speed is an essential parameter of gait analysis. Our study proposed a simple and accurate method to extract a mean gait speed during walking on a treadmill using only kinematic data from markers placed on the heels of the participants’ feet. This method provided an attractive, simple method that remains resistant to errors in treadmill calibration. In addition, this method required only two markers, since heel markers are essential to gait analysis, and the proposed method is robust enough to differentiate among various gait speeds (mean error <1%). 相似文献
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Prion colonization of secondary lymphoid organs (SLOs) is a critical step preceding neuroinvasion in prion pathogenesis. Follicular dendritic cells (FDCs), which depend on both tumor necrosis factor receptor 1 (TNFR1) and lymphotoxin β receptor (LTβR) signaling for maintenance, are thought to be the primary sites of prion accumulation in SLOs. However, prion titers in RML-infected TNFR1−/− lymph nodes and rates of neuroinvasion in TNFR1−/− mice remain high despite the absence of mature FDCs. Recently, we discovered that TNFR1-independent prion accumulation in lymph nodes relies on LTβR signaling. Loss of LTβR signaling in TNFR1−/− lymph nodes coincided with the de-differentiation of high endothelial venules (HEVs)—the primary sites of lymphocyte entry into lymph nodes. These findings suggest that HEVs are the sites through which prions initially invade lymph nodes from the bloodstream. Identification of HEVs as entry portals for prions clarifies a number of previous observations concerning peripheral prion pathogenesis. However, a number of questions still remain: What is the mechanism by which prions are taken up by HEVs? Which cells are responsible for delivering prions to lymph nodes? Are HEVs the main entry site for prions into lymph nodes or do alternative routes also exist? These questions and others are considered in this article. 相似文献
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Simona Delle Monache Patrizia Sanità Elena Trapasso Maria Rita Ursino Paola Dugo Marina Russo Nadia Ferlazzo Gioacchino Calapai Adriano Angelucci Michele Navarra 《PloS one》2013,8(4)
Based on the growing deal of data concerning the biological activity of flavonoid-rich natural products, the aim of the present study was to explore in vitro the potential anti-tumoral activity of Citrus Bergamia (bergamot) juice (BJ), determining its molecular interaction with cancer cells. Here we show that BJ reduced growth rate of different cancer cell lines, with the maximal growth inhibition observed in neuroblastoma cells (SH-SY5Y) after 72 hs of exposure to 5% BJ. The SH-SY5Y antiproliferative effect elicited by BJ was not due to a cytotoxic action and it did not induce apoptosis. Instead, BJ stimulated the arrest in the G1 phase of cell cycle and determined a modification in cellular morphology, causing a marked increase of detached cells. The inhibition of adhesive capacity on different physiologic substrates and on endothelial cells monolayer were correlated with an impairment of actin filaments, a reduction in the expression of the active form of focal adhesion kinase (FAK) that in turn caused inhibition of cell migration. In parallel, BJ seemed to hinder the association between the neural cell adhesion molecule (NCAM) and FAK. Our data suggest a mechanisms through which BJ can inhibit important molecular pathways related to cancer-associated aggressive phenotype and offer new suggestions for further studies on the role of BJ in cancer treatment. 相似文献
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