排序方式: 共有36条查询结果,搜索用时 0 毫秒
1.
Konovalova L. N. Strelnikova S. R. Zlobin N. E. Kharchenko P. N. Komakhin R. A. 《Applied Biochemistry and Microbiology》2021,57(7):800-807
Applied Biochemistry and Microbiology - The production of mesophilic protoplasts of potato (Solanum tuberosum L.) for transient gene expression is a required technological stage in the testing of... 相似文献
2.
Danilova E. D. Zlobin I. E. Kuznetsov V. V. Efimova M. V. 《Doklady. Biochemistry and biophysics》2021,499(1):228-232
Doklady Biochemistry and Biophysics - The effect of melatonin on growth parameters, the photochemical activity of photosystem II (PS II), the content of the main photosynthetic pigments, and lipid... 相似文献
3.
Zlobin I. E. Kartashov A. V. Kuznetsov Vl. V. 《Russian Journal of Plant Physiology》2019,66(4):591-596
Russian Journal of Plant Physiology - It is well known that excessive zinc accumulation is harmful to plant cells. Though, it is uncertain at which levels of intracellular availability zinc begins... 相似文献
4.
Activation of Notch-1 signaling maintains the neoplastic phenotype in human Ras-transformed cells 总被引:27,自引:0,他引:27
Weijzen S Rizzo P Braid M Vaishnav R Jonkheer SM Zlobin A Osborne BA Gottipati S Aster JC Hahn WC Rudolf M Siziopikou K Kast WM Miele L 《Nature medicine》2002,8(9):979-986
Truncated Notch receptors have transforming activity in vitro and in vivo. However, the role of wild-type Notch signaling in neoplastic transformation remains unclear. Ras signaling is deregulated in a large fraction of human malignancies and is a major target for the development of novel cancer treatments. We show that oncogenic Ras activates Notch signaling and that wild-type Notch-1 is necessary to maintain the neoplastic phenotype in Ras-transformed human cells in vitro and in vivo. Oncogenic Ras increases levels and activity of the intracellular form of wild-type Notch-1, and upregulates Notch ligand Delta-1 and also presenilin-1, a protein involved in Notch processing, through a p38-mediated pathway. These observations place Notch signaling among key downstream effectors of oncogenic Ras and suggest that it might be a novel therapeutic target. 相似文献
5.
Published data on both flora and phytocoenosis genesis and plant population dynamics are reviewed. Urbanized environment is rated as a stress factor for single plants and their communities. The change of plant population structure in cities and towns is analysed as the important indicator of the environment quality. The problems of phytoindication of environment quality in cities and towns for its optimization are considered. 相似文献
6.
Titov AA Shilenko IV Morozov AA Iarkov SP Zlobin VN 《Prikladnaia biokhimiia i mikrobiologiia》2012,48(2):249-256
Monoparametric immunoassay tests for detecting botulinum toxins types A and B and multiparametric assays for simultaneous detection of botulinum toxins type A and B have been developed. It is shown that the sensitivity of assays is affected by the size of nanoparticles of colloidal gold used as a marker of antibodies, load intensity of antibodies of colloidal gold in conjugates, the type of analytical membranes, as well as the chemical composition of buffer solutions used for the storage of conjugates and immunoassay analysis. The detection limit of monoparametric immunoassay tests is 0.5 ng/ml; that of multiparametric assays, 5.0 ng/ml. The developed immunoassay can be used for rapid assay of product quality, for grade control of botulinum toxins in pharmaceuticals, and environmental monitoring. 相似文献
7.
Yu. V. Ivanov I. E. Zlobin A. V. Kartashov P. P. Pashkovskiy Vl. V. Kuznetsov 《Russian Journal of Plant Physiology》2018,65(4):532-540
The idea that water deficit strengthening induces concerted changes of plant physiological parameters is rather widespread. However, such changes are often difficult to identify due to challenges in establishments and maintenance of required water stress intensities using solid substrates. Therefore, we exposed Scots pine (Pinus sylvestris L.) seedlings to the range of water potentials from–0.15 to–1.5 MPa in PEG-water culture to identify the series of physiological parameters differently sensitive to water stress. We observed that even mild water stress (–0.15 MPa) inhibited root elongation, which could be one of the main pine seedlings vulnerabilities under drought. Active accumulation of osmolytes was already induced by mild water deficit and further increased with water stress severity. Plant fresh biomass growth sensitivity was more related to changes of relative water content (RWC) than to changes in tissue water content or dry weight accumulation. Plants were able to grow and accumulate dry weight down to–0.5 MPa, but lower medium water potentials (–1.0 and–1.5 MPa) suppressed growth and heavily damaged root cells, as judged from many-fold increase of Ca2+ content in roots. Chlorophyll a content was surprisingly sensitive to water stress, while carotenoids level was increased under severe stress conditions. In conclusion, the experimental system with stepwise water potential values allowed us to analyze the sensitivity scale of a range of P. sylvestris physiological processes to water stress. It was largely similar to those described earlier for other plant species, but its peculiarities were high sensitivity of root elongation, marked resistance of biomass growth to water deficit and well-developed ability to osmotic adjustment. 相似文献
8.
9.
Ivanov Y. V. Zlobin I. E. Kartashov A. V. Savochkin Y. V. Kuznetsov Vl. V. 《Russian Journal of Plant Physiology》2019,66(3):440-449
Russian Journal of Plant Physiology - Plant growth is the physiological process that is generally the most affected by drought, and growth inhibition is one of the main contributors to ecosystem... 相似文献
10.
A. A. Zlobin E. A. Martinson S. G. Litvinets R. G. Ovodova Yu. S. Ovodov 《Russian Journal of Bioorganic Chemistry》2014,40(2):193-197
Polysaccharide fractions SAcI and SAcII were isolated from callus tissues of rowan tree stems. The SAcI fraction was shown to contain compounds belonging to the arabinogalactan II group. The SAcII fraction, called sorban, comprised pectic polysaccharides composing the protopectin complex of the cell wall callus. The SAcII fraction was found to contain a large amount of galacturonic acid residues and a set of neutral sugars characteristic of rhamnogalacturonan I. The composition and properties allowed a suggestion that the sorban backbone is mainly formed by 1,4-α-D-galactopyranosyluronic acid residues, while the neutral sugars are represented by 1,4-linked glucopyranose and xylopyranose residues, 1,5-linked arabinofuranose, 1,6-linked galactopyranose and mannofuranose residues as well as terminal glucopyranose and xylopyranose residues. The callus growth was shown to be associated with nearly a constant content of galacturonic acid and neutral sugar residues in sorban (fraction SAcII). 相似文献