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Md Dilshad Manzar Mohammad Muntafa Rajput Wassilatul Zannat Seithikurippu R. Pandi-Perumal Ahmed S. BaHammam M. Ejaz Hussain 《PloS one》2016,11(3)
Purpose
To study spontaneous K-complex (KC) densities during slow-wave sleep. The secondary objective was to estimate intra-non-rapid eye movement (NREM) sleep differences in KC density.Materials and Methods
It is a retrospective study using EEG data included in polysomnographic records from the archive at the sleep research laboratory of the Centre for Physiotherapy and Rehabilitation Sciences, Jamia Millia Islamia, India. The EEG records of 4459 minutes were used. The study presents a manual identification investigation of KCs in 17 healthy young adult male volunteers (age = 23.82±3.40 years and BMI = 23.42±4.18 kg/m2).Results
N3 had a higher KC density than N2 (Z = -2.485, p = 0.013) for all of the probes taken together. Four EEG probes had a higher probe-specific KC density during N3. The inter-probe KC density differed significantly during N2 (χ2 = 67.91, p < .001), N3 (χ2 = 70.62, p < .001) and NREM (χ2 = 68.50, p < .001). The percent distribution of KC decreased uniformly with sleep cycles.Conclusion
The inter-probe differences during N3 establish the fronto-central dominance of the KC density regardless of sleep stage. This finding supports one local theory of KC generation. The significantly higher KC density during N3 may imply that the neuro-anatomical origin of slow-wave activity and KC is the same. This temporal alignment with slow-wave activity supports the sleep-promoting function of the KC. 相似文献2.
Md. Dilshad Manzar Wassilatul Zannat Jamal Ali Moiz David Warren Spence Seithikurippu R. Pandi-Perumal Ahmed S. Bahammam 《Biological Rhythm Research》2016,47(6):851-864
The Pittsburgh Sleep Quality Index (PSQI) is a rigorously validated questionnaire with extensive use in sleep assessment. Findings from numerous factor analytic studies of the PSQI have been interpreted to support a heterogeneous factor structure model for the test. Nevertheless, the literature continues to lack a focused evaluation of whether this heterogeneous factor structure is justified. A consideration of this issue led to a conclusion that a closer analysis of the PSQI’s factor structure was merited. To address this need a comparative confirmatory factor analysis for assessing the performance of the accepted factors models of the PSQI was conducted. A sample of university students (n = 418), age = 20.92 ± 1.81 years, BMI = 23.30 ± 2.57 kg/m2 completed the multi-structured sleep survey at Jamia Millia Islamia, New Delhi, India. Seventeen putative factor structures (three 1-Factor, eight 2-Factor, and six 3-Factor) of the PSQI from the existing literature were selected for analysis. Fourteen models (82.35%) had almost similar values for model fit indices. Two models were misfits, and one model was a poor fit. The two misfit models incorporated gender and age as covariates. The third poor fit model was used to produce a unique path diagram, which made it distinct from the remaining 16 models. The overlapping values in the fit range of the model fit indices did not support the often projected heterogeneous factor structures of the PSQI for the vast majority of the models. 相似文献
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Morphological comparison among Drosophila lini and its two new sibling species (Diptera: Drosophilidae) 总被引:2,自引:0,他引:2
Morphological differences are investigated using several culture strains of three sibling species collected from Taiwan and Guangdong in China and Pyinoolwin and Yangon in Myanmar. Careful examination of male terminalia reveals distinguishable differences in the paramere and the aedeagal basal process among the three species. In addition, a number of quantitative characters are compared. Kruskal-Wallis tests with Bonferroni correction, which are carried out separately for each sex, detect significant differences in 15 characters, of which two are male-specific, among the three species. Canonical discriminant analysis using these characters reveals that the three species can be distinguished from each other with high confidence for both sexes. The results clearly show the presence of three good species, Drosophila (Sophophora) lini Bock & Wheeler, 1972 and its two new siblings. The new species are described as Drosophila (Sophophora) ohnishii sp. nov. from Pyinoolwin and Drosophila (Sophophora) ogumai sp. nov. from Yangon. The morphological differentiation among the three sibling species does not coincide with the degree of reproductive isolation (based on a previous study). The premating isolation pattern suggests two possibilities that premating isolation has been evolved or reinforced in sympatric populations between D. ohnishii and D. lini and between D. ohnishii and D. ogumai or that it has evolved in a very restricted local population of D. ohnishii, possibly by a few mutations. 相似文献
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The knowledge of sleep evaluation and its regulation processes has evolved dramatically over the last half-century. Sleep state and the preoccupied view of its obligation to perform positive function for the organism have kept enthusiastic research flourishing. The restoration of macromolecular synthesis and repair players, energy conservation, neural plasticity and synaptogenesis are cellular and biochemical-level functional implications of sleep. The demarcation between molecular, cellular and systemic strata is not mutually exclusive at organism level. Sleep functions have been researched with their focus at each of these strata. The review discusses the systemic-level functions of sleep in brief with special reference to respiration, reproduction, digestion, cardiovascular, endocrine, immune and integumentary systems. Sleep and physiological system relations are usually bidirectional and are operationally mediated by intercellular message transmitters like hormones, cytokines and/or continuum of direct anatomical connections with the neuroanatomy of sleep management. 相似文献
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