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C Crone J Frokjaer-Jensen JJ Friedman O Christensen 《The Journal of general physiology》1978,71(2):195-220
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Gale W. Rafter 《Biological trace element research》1982,4(2-3):191-197
Leukocytes incubated with Cu(II) showed a decrease in both glutathione reductase activity and reduced glutathione content.
The glucose 6-phosphate dehydrogenase activity under the same conditions was not affected. Serum albumin added to mixtures
prevented the loss of enzyme activity, whiled-penicillamine andl-histidine had little effect. Prior oxidation of the cell-reduced glutathione did not diminish the enzyme inhibitory action
of Cu(II). The amount of regeneration of reduced glutathione in leukocytes previously treated with diamide to oxidize their
reduced glutathione was a function of Cu(II) concentration in the media. No evidence was obtained that elevated serum ceruloplasmin
levels in rabbits, nor incubation of leukocytes in vitro with ceruloplasmin, affect leukocyte glutathione reductase activity.
It was proposed that the major mechanism by which copper affects glutathione metabolism in leukocytes is by inhibition of
glutathione reductase. 相似文献
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Structured host-choice and no-choice tests were conducted to help clarify the host plant interactions of an insect herbivore that is simultaneously seen as broadly polyphagous and pestiferous (in Africa) and host restricted/beneficial (in Australia). The research reported here involves specification of the host range of the invasive population of Scirtothrips aurantii found on Bryophyllum in Australia and included tests involving three separate lists of plant species considered to have the potential for thrips attack (plants of horticultural concern, native species at risk of attack and species listed for screening in the search for specialist B. delagoense biocontrol agents). This procedure was developed specifically to deal with the S. aurantii situation in Australia. Because the test species is already present in the field, the conclusions from the tests could be evaluated independently against field sampling results. Host testing revealed that the fundamental host range of the Bryophyllum population of S. aurantii includes Macadamia integrifolia, Mangifera indica and Kalanchoe blossfeldianna. However, the choice tests (involving B. delagoense) and a field survey of Man. indica demonstrated conclusively that the realised host range of S. aurantii in the field is restricted to Crassulaceae. We recommend that host testing of generalist insects not be discounted out of hand (for biological control) because of their perceived polyphagy. Any evidence of populations being strongly associated with the weed species of interest (through quantified host association studies in the native range) suggests further scrutiny of that population is warranted, by means of the host testing methods developed here and in conjunction with appropriate tests of the population’s species status. 相似文献
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P. Rafter N McHugh T. Pabiou D.P. Berry 《Animal : an international journal of animal bioscience》2022,16(8):100604
Monitoring the rate of change in inbreeding and genetic diversity within a population is important to guide breeding programmes. Such interest stems from the impact of loss in genetic diversity on sustainable genetic gain but also the impact on performance (i.e. inbreeding depression). The objective of the present study was to evaluate trends in inbreeding and genetic diversity in 43 066 Belclare, 120 753 Charollais, 22 652 Galway, 78 925 Suffolk, 187 395 Texel, and 19 821 Vendeen purebred sheep. The effective population size for each of the six breeds was between 116.0 (Belclare population) and 314.8 (Charollais population). The Charollais population was the most genetically diverse with the greatest number of effective founders, effective ancestors, and effective founder genomes; conversely, the Belclare was the least genetically diverse population with the fewest number of effective founders, effective ancestors, and effective founder genomes for each of the six breeds investigated. Overall, the effective population sizes and the total genetic diversity within each of the six breeds were above the minimum thresholds generally considered to be required for the long-term viability of a population. 相似文献