全文获取类型
收费全文 | 823篇 |
免费 | 62篇 |
出版年
2023年 | 12篇 |
2022年 | 9篇 |
2021年 | 44篇 |
2020年 | 19篇 |
2019年 | 22篇 |
2018年 | 23篇 |
2017年 | 10篇 |
2016年 | 28篇 |
2015年 | 49篇 |
2014年 | 40篇 |
2013年 | 51篇 |
2012年 | 77篇 |
2011年 | 50篇 |
2010年 | 29篇 |
2009年 | 41篇 |
2008年 | 43篇 |
2007年 | 26篇 |
2006年 | 35篇 |
2005年 | 27篇 |
2004年 | 17篇 |
2003年 | 27篇 |
2002年 | 17篇 |
2001年 | 11篇 |
2000年 | 8篇 |
1999年 | 12篇 |
1997年 | 5篇 |
1996年 | 5篇 |
1995年 | 6篇 |
1994年 | 8篇 |
1993年 | 6篇 |
1992年 | 6篇 |
1991年 | 6篇 |
1990年 | 4篇 |
1989年 | 6篇 |
1988年 | 4篇 |
1987年 | 6篇 |
1986年 | 4篇 |
1985年 | 5篇 |
1983年 | 5篇 |
1982年 | 4篇 |
1979年 | 4篇 |
1978年 | 3篇 |
1977年 | 6篇 |
1976年 | 3篇 |
1972年 | 3篇 |
1971年 | 5篇 |
1970年 | 5篇 |
1969年 | 5篇 |
1968年 | 6篇 |
1967年 | 4篇 |
排序方式: 共有885条查询结果,搜索用时 31 毫秒
1.
Dennis W. Jung Gerald P. Brierley 《Biochemical and biophysical research communications》1982,106(4):1372-1377
Heart mitochondria respiring in the presence of Pi release endogenous K+ to a sucrose medium when an uncoupler is added. The uncoupled mitochondria retain K+, however, if the oxidation of NAD(P)H is prevented by the addition of rotenone or antimycin. Addition of rotenone, once the uncoupler-dependent K+-efflux has been initiated, results in a rapid reduction of NAD(P) and a simultaneous decrease in permeability to K+. These changes are independent of respiration. The results suggest that a latent pathway for K+-permeability is present in the membrane, that it can be opened and closed reversibly, and that it reflects, either directly or indirectly, the redox status of mitochondrial pyridine nucleotides. The possible relationship of this putative pathway to those available for Ca2+ uptake and release is considered. 相似文献
2.
3.
4.
5.
Gerald P. Brierley Kemal Baysal Dennis W. Jung 《Journal of bioenergetics and biomembranes》1994,26(5):519-526
It is now well established that mitochondria contain three antiporters that transport monovalent cations. A latent, allosterically regulated K+/H+ antiport appears to serve as a cation-extruding device that helps maintain mitochondrial volume homeostasis. An apparently unregulated Na+/H+ antiport keeps matrix [Na+] low and the Na+-gradient equal to the H+-gradient. A Na+/Ca2+ antiport provides a Ca2+-extruding mechanism that permits the mitochondrion to regulate matrix [Ca2+] by balancing Ca2+ efflux against influx on the Ca2+-uniport. All three antiports have well-defined physiological roles and their molecular properties and regulatory features are now being determined. Mitochondria also contain monovalent cation uniports, such as the recently described ATP- and glibenclamide-sensitive K+ channel and ruthenium red-sensitive uniports for Na+ and K+. A physiological role of such uniports has not been established and their properties are just beginning to be defined. 相似文献
6.
7.
8.
Liam J. Hughes Oscar Morton Brett R. Scheffers David P. Edwards 《Biological reviews of the Cambridge Philosophical Society》2023,98(3):775-791
Wildlife trade is a key driver of extinction risk, affecting at least 24% of terrestrial vertebrates. The persistent removal of species can have profound impacts on species extinction risk and selection within populations. We draw together the first review of characteristics known to drive species use – identifying species with larger body sizes, greater abundance, increased rarity or certain morphological traits valued by consumers as being particularly prevalent in trade. We then review the ecological implications of this trade-driven selection, revealing direct effects of trade on natural selection and populations for traded species, which includes selection against desirable traits. Additionally, there exists a positive feedback loop between rarity and trade and depleted populations tend to have easy human access points, which can result in species being harvested to extinction and has the potential to alter source–sink dynamics. Wider cascading ecosystem repercussions from trade-induced declines include altered seed dispersal networks, trophic cascades, long-term compositional changes in plant communities, altered forest carbon stocks, and the introduction of harmful invasive species. Because it occurs across multiple scales with diverse drivers, wildlife trade requires multi-faceted conservation actions to maintain biodiversity and ecological function, including regulatory and enforcement approaches, bottom-up and community-based interventions, captive breeding or wildlife farming, and conservation translocations and trophic rewilding. We highlight three emergent research themes at the intersection of trade and community ecology: (1) functional impacts of trade; (2) altered provisioning of ecosystem services; and (3) prevalence of trade-dispersed diseases. Outside of the primary objective that exploitation is sustainable for traded species, we must urgently incorporate consideration of the broader consequences for other species and ecosystem processes when quantifying sustainability. 相似文献
9.
10.