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1.
Juliusz Perkowski Jerzy Chełkowski Ronald D. Plattner Piotr Goliński 《Mycotoxin Research》1991,7(2):115-120
Maize cobs withFusarium ear rot were collected at 1986 season and five infected byFusarium graminearum were analyzed for presence of triohothecenes and zearalenone. Collected material was subsampled forFusarium damaged kernels and corresponding axial stems and healthy looking kernels. All investigated cobs contained deoxynivalenol (DON) (range 18.0–131.5 mg/kg) and zearalenone (ZEA) (range 0.38–2.17 mg/kg), in four cobs 15-acetyl-deoxynivalenol (15-AcDON) (range 5.2–6.2 mg/kg) was present and two cobs besides three all metabolites contained 3-acetyl-deoxynivalenol (3-AcD0N) (range 0.5–0.8 mg/kg).The average of individual toxins amount in axial stems: in mg/kg was equal to: DON — 110.36, ZEA — 4.57, 15-AcD0N — 16.66, and 3-AcD0N — 1.32.Fusarium damaged kernels contained in average the following amount (mg/kg) of: DON 77.00, ZEA 0.98, 15-AcD0N 3.78 and 3-AcD0N 0.06. Healthy looking kernels contained DON 1.96 mg/kg and ZEA 0.07 mg/kg only. Cooccurrence of 3-AcDON and 15-AcDON in two samples was an interesting finding. The amount of DON in total cob was highly correlated (r = 0.94) with percentage ofFusarium damaged kernels in given ear. 相似文献
2.
P Goliński S Wnuk J Che?kowski A Visconti M Schollenberger 《Applied and environmental microbiology》1986,51(4):743-745
A compound very similar to the mycotoxin citrinin was observed on thin-layer chromatographic plates during the screening analysis of grain extracts. This compound was produced by 22 of the tested Fusarium avenaceum (Corda ex Fries) Sacc. strains isolated from wheat, triticale, barley, corn, and potatoes. A chemical test confirmed the presence of an unknown compound, which was given the preliminary name of antibiotic Y (indicating yellow fluorescence). The following properties of the new metabolite are described: spectroscopic (UV, infrared, proton nuclear magnetic resonance, fluorescence, and mass spectrometry), phytotoxic, antibiotic (inhibitory effect of bacterial growth), and toxic (toxicity to Artemia salina, chicken embryos, and mouse fibroblasts). Elemental analysis of the compound showed that it had the general formula C15H10O8, in agreement with the mass spectrometric finding that the molecular ion had a molecular weight of 318. The structure of the compound is presently under study. 相似文献
3.
Biserka Kojić-Prodić Živa Ružić-Toroš Ljubo Golič Branko Brdar Jože Kobe 《Biochimica et Biophysica Acta (BBA) - Gene Structure and Expression》1982,698(2):105-110
The crystal and molecular structure of one imidazo[1,2-a]-s-triazine nucleoside and its antiviral activity are described. The crystal structure of 2-amino-8-(β-d-ribofuranosyl)imidazo-[1,2-a]-s-triazin-4-one monohydrate (C10H13N5O5·H2O) was solved by X-ray counter data. The compound crystallizes in the monoclinic space group P21 with cell dimensions a = 7.353 (1), b = 6.465 (1), c = 13.701 (1) Å, β = 104.64 (1)°. The structure was solved by direct methods and refined by full matrix least-squares technique to a final value of the conventional R-factor of 0.049 using 1998 observed intensities. The orientation of the base relative to the sugar ring defined in terms of rotation about the C(1′)-N(8) glycosyl bond is anti (47.8°). The ribose moiety exhibits C(2′)-endo, 2E conformation. The conformation around C(4′)-C(5′) is gauche?. Molecular packing is dominated by hydrogen bonds. Base stacking occurs long the b axis. 5-Aza-7-deazaguanosine has shown a marked antiviral activity in vitro against herpes simplex virus despite the fact that N(3) is effective as the hydrogen acceptor only. 相似文献
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Oghbaei Hajar Hosseini Leila Farajdokht Fereshteh Rahigh Aghsan Sepideh Majdi Alireza Sadigh-Eteghad Saeed Sandoghchian Shotorbani Siamak Mahmoudi Javad 《Molecular biology reports》2021,48(8):5881-5887
Molecular Biology Reports - The current study was set to assess the effect of heat stress exposure on oxidative stress, apoptosis, and endoplasmic reticulum stress markers in the cerebellum of male... 相似文献
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7.
Fereshteh Khorrami Oruj Valizadegan Maryam Forouzan Asmar Soleymanzade 《Archives Of Phytopathology And Plant Protection》2013,46(13-14):685-695
AbstractRed flour beetle, Tribolium castaneum Herbst (Coleoptera: Tenebrionidae) is a prominent pest of stored products particularly cereal flour. Since resistance of this pest to common chemical insecticides is well documented, we were examined the synergistic/antagonistic interaction between Satureja hortensis L., Trachyspermum ammi L., Ziziphora tenuior L., Cuminum cyminum L. and Foeniculum vulgare Miller essential oils, ethanolic extracts and powders with Diatomaceous earth (DE) against T. castaneum adults under laboratory conditions at 27 ± 1 °C, 65 ± 5% RH and continuous darkness. We assayed repellency of ethanolic extracts and essential oils of mentioned plants on the pest. Results showed that DE had high toxicity to the pest. Plant essential oils and ethanolic extracts (except ziziphora) synergized the performance of DE. Nevertheless, plant powders elicited antagonistic effects (except ziziphora that exhibited synergistic effect). The most repellent EO and extract was cumin which exhibited mean repellency value on adult insect equivalent to 92.58 and 51.47%, respectively. 相似文献
8.
Reza Ebrahimzadeh-Vesal Seyed kianush Hosseini Fereshteh Rezakhanlu Pupak Derakhshandeh-Peykar 《Reports of Biochemistry & Molecular Biology》2013,2(1):52-55
Holt-Oram syndrome (HOS) is a developmental disorder inherited in an autosomal-dominant pattern. Affected organs are the heart and forelimbs with upper extremity skeletal defects and congenital heart malformation. In this study we present three cases of HOS in the same family. In one of these three individuals we detected a transition of C to T (CTG-GTT, V205V) in exon 7 of the TBX5 gene. This nucleotide change causes no amino acid change and potential pathologic effects remain unknown.Key Words: Holt-Oram syndrome, Congenital heart malformation, TBX5 gene 相似文献
9.
Liver alteration and hematological and serum biochemical responses of common carp,Cyprinus carpio Linnaeus, 1758, following long‐term feeding of pistachio (Pistacia vera) green hull extract as a source of natural phenol 下载免费PDF全文
J. Motamedi‐Tehrani E. Ebrahimi‐Dorcheh P. Malekpouri S. A. H. Goli 《Zeitschrift fur angewandte Ichthyologie》2016,32(5):906-912
This study was conducted to investigate the effect of pistachio green hull extract (PGHE) on hematological and serum biochemical changes in common carp, Cyprinus carpio. Three hundred common carp (11.65 ± 1.65 g) were fed one of five different dietary treatments (with three replications) containing 0, 0.5, 1.5, 4.5 or 9 g PGHE kg?1diet for ten continuous weeks. Each tank had a 90‐L capacity and water flow rate of about 500 ml min_1.Total phenolic compounds of the different diets differed significantly (P < 0.001) according to the amount of PGHE. At the end of experiment, six fish were removed randomly from each treatment. Blood samples were taken for hematological and serum biochemical analyses at room temperature. Liver tissue samples were processed for histology and stained by H&E. The results indicated that all doses of tested PGHE induced no significant changes in hematocrit, hemoglobin, or erythrocytes, nor alkaline phosphatase, alanine transaminase, lactate dehydrogenase, total protein, albumin, globulin, triglycerides, low‐density lipoprotein, high‐density lipoprotein, glucose or cholesterol in the serum. Leukocytes were higher (P < 0.01) in fish fed a 1.5, 4.5, or 9 g PGHE kg?1 diet when compared to the 0.5 g PGHE kg?1 diet group or the control. Serum aspartate transaminase in treatments containing a 4.5 or 9 g PGHE kg?1 diet was significantly (P < 0.001) higher in comparison with the control. Liver histology showed focal necrosis, cytoplasm degeneration, lateral nuclei and an increase in Kupffer cells following PGHE administrations. The results of this trial indicated that although there were no significant changes in most hematological and biochemical parameters, PGHE could induce some adverse pathological effects on liver tissue. 相似文献
10.
Mirosław Mleczek Paweł Rutkowski Przemysław Niedzielski Piotr Goliński Monika Gąsecka Tomisław Kozubik 《International journal of phytoremediation》2016,18(11):1086-1095
The aim of the study was to estimate the ability of ten tree and bush species to tolerate and accumulate Cd, Cu, Pb, Zn, and As species [As(III), As(V), and total organic arsenic] in industrial sewage sludge extremely contaminated with arsenic (almost 27.5 g kg?1) in a pot experiment. The premise being that it will then be possible to select the most promising tree/bush species, able to grow in the vicinity of dams where sewage sludge/flotation tailings are used as landfill. Six of the ten tested tree species were able to grow on the sludge. The highest content of total As was observed in Betula pendula roots (30.0 ± 1.3 mg kg?1 DW), where the dominant As species was the toxic As(V). The highest biomass of Quercus Q1 robur (77.3 § 2.6 g) and Acer platanoides (76.0 § 4.9 g) was observed. A proper planting of selected tree species that are able to thrive on sewage sludge/flotation tailings could be an interesting and promising way to protect dams. By utilizing differences in their root systems and water needs, we will be able to reduce the risk of fatal environmental disasters. 相似文献