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排序方式: 共有206条查询结果,搜索用时 15 毫秒
1.
Fabrizio Villani Milena Galimberti Elena Monti Francesco Piccinini Enrica Lanza Annalinda Rozza Luigia Favalli Paola Poggi Franco Zunino 《Free radical research》1990,11(1):145-151
The effects of two sulfhydryl compounds, glutathione (GSH) and N-acetylcysteine (NAC), on the cardiotoxicity of doxorubicin (DXR) were tested on in vitro and in vivo models. DXR was administered to rats as 4 weekly i.v. doses of 3mg/kg. GSH (1.5 mmoles/kg), given i.v. 10 min before and 1 hr after DXR, was found to prevent the development of the delayed cardiotoxic effects of DXR, as assessed by electrocardiographic and mechanical parameters, as well as by histological examination of left ventricular preparations. In contrast, equimolar oral doses of NAC (1 hr before and 2hrs after DXR) were found to be ineffective. Both GSH and NAC prevented the negative inotropic effect produced by DXR on isolated rat atria. A good correlation exists between the cardioprotective effects of the two agents and their ability to enhance the non-protein sulfhydryl group content of the myocardium. Differences observed in vivo between GSH and NAC might be accounted for by pharmacokinetic factors. 相似文献
2.
We present a list of Italian freshwater and marine Oligochaeta in the families Lumbriculidae, Haplotaxidae, Tubificidae, Naididae, Propappidae, Criodrilidae, and Lumbricidae, representing 57 genera and 130 species. Published data reflect the incomplete knowledge of the Italian oligochaete fauna, restricted to certain geographical areas. Subterranean aquatic and marine fauna are of particular interest as these have been studied the least. We provide a comprehensive review of the Naididae including, for the first time, southern Italy and the islands of Sicily and Sardinia. The distribution of species is discussed and taxonomic problems arising from the morphological variability of Italian material are examined. 相似文献
3.
C. Poggi Pollini L. Giunchedi E. Seemüller K.-H. Lorenz 《Journal of Phytopathology》1994,142(2):115-121
Mycoplasma-like organisms (MLOs) were constantly detected by the DAPI technique and by restriction fragment length polymorphism (RFLP) analysis of PCR-amplified DNA in trees of Pyrus pyrifolia cvs Hosui and Kosui grafted on P. communis, seedlings rootstock with symptoms similar to the slow form of pear decline. These symptoms included upward curling of the leaves along the midrib. Leaves were abnormally thick and later turned reddish while major veins became swollen and brown. Trees with symptoms were usually 4–5 years old and were growing in the major pear areas of central Italy. The incidence of affected trees was particularly high in one orchard adjacent to a pear orchard strongly affected with the slow form of pear decline. In this case the distribution pattern of affected Nashi trees suggests that the causal agent was introduced from the adjacent pear orchard by an aerial vector. Although oriental pears are well-known hosts of the pear-decline agent when used as rootstocks of French cultivars, this is the first report of pear decline in P. pyrifolia varieties. 相似文献
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5.
Maria Antonietta Zoroddu Michelina Fruianu Roberto Dallocchio Andreina Masia 《Biometals》1996,9(1):91-97
Vanadium uptake by whole cells and isolated cell walls of the yeast Saccharomyces cerevisiae was studied. When orthovanadate was added to wild-type S. cerevisiae cells growing in rich medium, growth was inhibited as a function of the VO4
3- concentration and the growth was completely arrested at a concentration of 20 mM of VO4
3- in YEPD. Electron paramagnetic resonance (EPR) spectroscopy was used to obtain structural and dynamic information about the cell-associated paramagnetic vanadyl ion. The presence of EPR signals indicated that vanadate was reduced by whole cells to the vanadyl ion. On the contrary, no EPR signals were detected after interaction of vanadate with isolated cell walls. A mobile and an immobile species associated in cells with small chelates and with macromolecular sites, respectively, were identified. The value of rotational correlation time
r indicated the relative motional freedom at the macromolecular site. A strongly immobilized vanadyl species bound to polar sites mainly through coulombic attractions was detected after interaction of VO2+ ions with isolated cell walls. 相似文献
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7.
Spartaco Gippoliti Andreina D’Alessandro 《Der Zoologische Garten (in deutscher Sprache / in German)》2013,82(3-4):113-128
This work reviews nearly 90 years of ape keeping and housing at the Giardino Zoologico in Rome, and offers an overview of the scientific research carried out on these primates. It may thus contribute to a better historical knowledge of primate zoo management in Italy. Furthermore, particular attention is paid to morphological aspects in orangutan physical development that should deserve further research. 相似文献
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9.
Stefano Minguzzi Federica Terlizzi Chiara Lanzoni Carlo Poggi Pollini Claudio Ratti 《PloS one》2016,11(1)
Many efforts have been made to develop a rapid and sensitive method for phytoplasma and virus detection. Taking our cue from previous works, different rapid sample preparation methods have been tested and applied to Candidatus Phytoplasma prunorum (‘Ca. P. prunorum’) detection by RT-qPCR. A duplex RT-qPCR has been optimized using the crude sap as a template to simultaneously amplify a fragment of 16S rRNA of the pathogen and 18S rRNA of the host plant. The specific plant 18S rRNA internal control allows comparison and relative quantification of samples. A comparison between DNA and RNA contribution to qPCR detection is provided, showing higher contribution of the latter. The method presented here has been validated on more than a hundred samples of apricot, plum and peach trees. Since 2013, this method has been successfully applied to monitor ‘Ca. P. prunorum’ infections in field and nursery. A triplex RT-qPCR assay has also been optimized to simultaneously detect ‘Ca. P. prunorum’ and Plum pox virus (PPV) in Prunus. 相似文献
10.
Shanti Souriant Luciana Balboa Maeva Dupont Karine Pingris Denise Kviatcovsky Céline Cougoule Claire Lastrucci Aicha Bah Romain Gasser Renaud Poincloux Brigitte Raynaud-Messina Talal Al Saati Sandra Inwentarz Susana Poggi Eduardo Jose Moraña Pablo González-Montaner Marcelo Corti Bernard Lagane Christel Vérollet 《Cell reports》2019,26(13):3586-3599.e7